Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Body Composition Growth Patterns in Early Infancy: A Latent Class Trajectory Analysis of the Ethiopian iABC Birth Cohort

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Association between ketosis and changes in appetite markers with weight loss following a very low-energy diet

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Gut Mucosal Gene Expression and Metabolic Changes After Roux-en-Y Gastric Bypass Surgery

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. BMI and Labor Market Participation: A Cohort Study of Transitions Between Work, Unemployment, and Sickness Absence

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Overweight Patterns Between Childhood and Early Adulthood and Esophageal and Gastric Cardia Adenocarcinoma Risk

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Physiological predictors of weight regain at 1-year follow-up in weight-reduced adults with obesity

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The quality of dietary carbohydrate and fat is associated with better metabolic control in persons with type 1 and type 2 diabetes

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Omega-3 fatty acids and risk of cardiovascular disease in Inuit: First prospective cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

OBJECTIVE: The objective of this study was to identify subgroups with distinct fat and fat-free growth patterns in the first 6 months of life and describe predictors of these different patterns.

METHODS: A total of 510 apparently healthy Ethiopian infants were followed from birth to 6 months of age. Each infant had at least three and up to six repeated measurements of fat and fat-free mass using air-displacement plethysmography. Latent class trajectory analyses were used to categorize infants in groups with distinct body composition patterns.

RESULTS: Four distinct fat mass and two fat-free mass growth patterns were identified. Of the infants measured, 5% presented a delayed fat growth pattern and 3% presented a catch-up fat growth pattern involving low birth weight but a significant fat growth velocity from 2.5 to 6 months. A large class had a high fat level at birth and an accelerated fat growth pattern in early infancy. Fat-free growth was represented by two distinct classes with less variability. Catch-up growth was primarily seen in fat mass.

CONCLUSIONS: We identified distinct patterns of delayed, catch-up, and accelerated fat growth in early infancy. This variability is not detected in regular anthropometric assessment and could be a mechanism linking early growth with later obesity and cardiometabolic risk.

Original languageEnglish
JournalObesity (Silver Spring, Md.)
Volume26
Issue number7
Pages (from-to)1225-1233
Number of pages8
ISSN1930-7381
DOIs
Publication statusPublished - Jul 2018

ID: 54333282