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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Blood-brain barrier permeability of normal appearing white matter in relapsing-remitting multiple sclerosis

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  1. European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)

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  2. Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System

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  3. Accessibility of cortical regions to focal TES: Dependence on spatial position, safety, and practical constraints

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  4. Coil profile estimation strategies for parallel imaging with hyperpolarized 13 C MRI

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  5. Inductive measurement and encoding of k-space trajectories in MR raw data

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Multiple sclerosis (MS) affects the integrity of the blood-brain barrier (BBB). Contrast-enhanced T1 weighted magnetic resonance imaging (MRI) is widely used to characterize location and extent of BBB disruptions in focal MS lesions. We employed quantitative T1 measurements before and after the intravenous injection of a paramagnetic contrast agent to assess BBB permeability in the normal appearing white matter (NAWM) in patients with relapsing-remitting MS (RR-MS).
Original languageEnglish
JournalP L o S One
Volume8
Issue number2
Pages (from-to)e56375
ISSN1932-6203
DOIs
Publication statusPublished - 2013

    Research areas

  • Adult, Blood-Brain Barrier, Brain, Case-Control Studies, Female, Gadolinium DTPA, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Multiple Sclerosis, Relapsing-Remitting, Permeability

ID: 41127010