Birth weight and prematurity for predicting type 2 diabetes mellitus: a prognostic review

Ishanka Weerasekara; Lea Styrmisdóttir; Martin Ringsten; Nicola Orsini; Carol Mukiira; Shantanu Sharma; Michelle Fiander; Ola Andersson; Allan A Vaag; Peter M Nilsson; Matteo Bruschettini

doi:10.1002/14651858.CD016154

Birth weight and prematurity for predicting type 2 diabetes mellitus: a prognostic review

Ishanka Weerasekara, Lea Styrmisdóttir, Martin Ringsten, Nicola Orsini, Carol Mukiira, Shantanu Sharma, Michelle Fiander, Ola Andersson, Allan A Vaag, Peter M Nilsson, Matteo Bruschettini^*

^*Corresponding author for this work

Steno Diabetes Center Copenhagen

Abstract

OBJECTIVES: This is a protocol for a Cochrane Review (prototype). The objectives are as follows: Primary objective To determine the prognostic value of birth weight (BW) and prematurity in predicting the incidence of type 2 diabetes mellitus (T2DM) later in life (among adults, adolescents, and children) compared to normal BW and full-term birth. Secondary objectives To determine the prognostic value of BW and prematurity in predicting the incidence rates of diabetic neuropathy, diabetic retinopathy, and diabetic nephropathy, later in life (among adults, adolescents, and children) compared to normal BW and full-term birth.

Original language	English
Journal	Cochrane Database of Systematic Reviews
Volume	9
Issue number	9
Pages (from-to)	CD016154
ISSN	1361-6137
DOIs	https://doi.org/10.1002/14651858.CD016154
Publication status	Published - 2 Sept 2025

Keywords

Humans
Diabetes Mellitus, Type 2/epidemiology
Infant, Newborn
Prognosis
Birth Weight
Infant, Premature
Adult
Diabetic Neuropathies/epidemiology
Adolescent
Diabetic Nephropathies/epidemiology
Child
Diabetic Retinopathy/epidemiology

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10.1002/14651858.CD016154

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title = "Birth weight and prematurity for predicting type 2 diabetes mellitus: a prognostic review",

abstract = "OBJECTIVES: This is a protocol for a Cochrane Review (prototype). The objectives are as follows: Primary objective To determine the prognostic value of birth weight (BW) and prematurity in predicting the incidence of type 2 diabetes mellitus (T2DM) later in life (among adults, adolescents, and children) compared to normal BW and full-term birth. Secondary objectives To determine the prognostic value of BW and prematurity in predicting the incidence rates of diabetic neuropathy, diabetic retinopathy, and diabetic nephropathy, later in life (among adults, adolescents, and children) compared to normal BW and full-term birth.",

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author = "Ishanka Weerasekara and Lea Styrmisd{\'o}ttir and Martin Ringsten and Nicola Orsini and Carol Mukiira and Shantanu Sharma and Michelle Fiander and Ola Andersson and Vaag, \{Allan A\} and Nilsson, \{Peter M\} and Matteo Bruschettini",

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doi = "10.1002/14651858.CD016154",

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TY - JOUR

T1 - Birth weight and prematurity for predicting type 2 diabetes mellitus

T2 - a prognostic review

AU - Weerasekara, Ishanka

AU - Styrmisdóttir, Lea

AU - Ringsten, Martin

AU - Orsini, Nicola

AU - Mukiira, Carol

AU - Sharma, Shantanu

AU - Fiander, Michelle

AU - Andersson, Ola

AU - Vaag, Allan A

AU - Nilsson, Peter M

AU - Bruschettini, Matteo

PY - 2025/9/2

Y1 - 2025/9/2

N2 - OBJECTIVES: This is a protocol for a Cochrane Review (prototype). The objectives are as follows: Primary objective To determine the prognostic value of birth weight (BW) and prematurity in predicting the incidence of type 2 diabetes mellitus (T2DM) later in life (among adults, adolescents, and children) compared to normal BW and full-term birth. Secondary objectives To determine the prognostic value of BW and prematurity in predicting the incidence rates of diabetic neuropathy, diabetic retinopathy, and diabetic nephropathy, later in life (among adults, adolescents, and children) compared to normal BW and full-term birth.

AB - OBJECTIVES: This is a protocol for a Cochrane Review (prototype). The objectives are as follows: Primary objective To determine the prognostic value of birth weight (BW) and prematurity in predicting the incidence of type 2 diabetes mellitus (T2DM) later in life (among adults, adolescents, and children) compared to normal BW and full-term birth. Secondary objectives To determine the prognostic value of BW and prematurity in predicting the incidence rates of diabetic neuropathy, diabetic retinopathy, and diabetic nephropathy, later in life (among adults, adolescents, and children) compared to normal BW and full-term birth.

KW - Humans

KW - Diabetes Mellitus, Type 2/epidemiology

KW - Infant, Newborn

KW - Prognosis

KW - Birth Weight

KW - Infant, Premature

KW - Adult

KW - Diabetic Neuropathies/epidemiology

KW - Adolescent

KW - Diabetic Nephropathies/epidemiology

KW - Child

KW - Diabetic Retinopathy/epidemiology

UR - https://www.scopus.com/pages/publications/105015032590

U2 - 10.1002/14651858.CD016154

DO - 10.1002/14651858.CD016154

M3 - Journal article

C2 - 40891492

SN - 1361-6137

VL - 9

SP - CD016154

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

IS - 9

ER -

Birth weight and prematurity for predicting type 2 diabetes mellitus: a prognostic review

Abstract

Keywords

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