Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease

Alaa El-Hussuna; Jens Andersen; Thue Bisgaard; Per Jess; Mads Henriksen; Jacob Oehlenschlager; Ole Thorlacius-Ussing; Gunnar Olaison

doi:10.3109/00365521.2012.660540

Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease

Alaa El-Hussuna, Jens Andersen, Thue Bisgaard, Per Jess, Mads Henriksen, Jacob Oehlenschlager, Ole Thorlacius-Ussing, Gunnar Olaison

75 Citations (Scopus)

Abstract

There are concerns that biologic treatments or immunomodulation may negatively influence anastomotic healing. This study investigates the relationship between these treatments and anastomotic complications after surgery for Crohn's disease.

Original language	English
Journal	Scandinavian Journal of Gastroenterology
Volume	47
Issue number	6
Pages (from-to)	662-8
Number of pages	7
ISSN	0036-5521
DOIs	https://doi.org/10.3109/00365521.2012.660540
Publication status	Published - 2012

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Anastomosis, Surgical
Anastomotic Leak
Anti-Inflammatory Agents
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Child
Colon
Crohn Disease
Female
Glucocorticoids
Humans
Immunoglobulin Fab Fragments
Immunosuppressive Agents
Intestine, Small
Intraabdominal Infections
Logistic Models
Male
Middle Aged
Multivariate Analysis
Polyethylene Glycols
Postoperative Complications
Prednisolone
Retrospective Studies
Risk Factors
Surgical Wound Dehiscence
Young Adult

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El-Hussuna, A., Andersen, J., Bisgaard, T., Jess, P., Henriksen, M., Oehlenschlager, J., Thorlacius-Ussing, O., & Olaison, G. (2012). Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease. Scandinavian Journal of Gastroenterology, 47(6), 662-8. https://doi.org/10.3109/00365521.2012.660540

El-Hussuna, A, Andersen, J, Bisgaard, T, Jess, P, Henriksen, M, Oehlenschlager, J, Thorlacius-Ussing, O & Olaison, G 2012, 'Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease', Scandinavian Journal of Gastroenterology, vol. 47, no. 6, pp. 662-8. https://doi.org/10.3109/00365521.2012.660540

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abstract = "There are concerns that biologic treatments or immunomodulation may negatively influence anastomotic healing. This study investigates the relationship between these treatments and anastomotic complications after surgery for Crohn's disease.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Anastomosis, Surgical, Anastomotic Leak, Anti-Inflammatory Agents, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Child, Colon, Crohn Disease, Female, Glucocorticoids, Humans, Immunoglobulin Fab Fragments, Immunosuppressive Agents, Intestine, Small, Intraabdominal Infections, Logistic Models, Male, Middle Aged, Multivariate Analysis, Polyethylene Glycols, Postoperative Complications, Prednisolone, Retrospective Studies, Risk Factors, Surgical Wound Dehiscence, Young Adult",

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AU - El-Hussuna, Alaa

AU - Andersen, Jens

AU - Bisgaard, Thue

AU - Jess, Per

AU - Henriksen, Mads

AU - Oehlenschlager, Jacob

AU - Thorlacius-Ussing, Ole

AU - Olaison, Gunnar

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KW - Aged

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KW - Anastomosis, Surgical

KW - Anastomotic Leak

KW - Anti-Inflammatory Agents

KW - Antibodies, Monoclonal

KW - Antibodies, Monoclonal, Humanized

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KW - Colon

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KW - Female

KW - Glucocorticoids

KW - Humans

KW - Immunoglobulin Fab Fragments

KW - Immunosuppressive Agents

KW - Intestine, Small

KW - Intraabdominal Infections

KW - Logistic Models

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KW - Middle Aged

KW - Multivariate Analysis

KW - Polyethylene Glycols

KW - Postoperative Complications

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KW - Retrospective Studies

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DO - 10.3109/00365521.2012.660540

M3 - Journal article

C2 - 22486168

SN - 0036-5521

VL - 47

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EP - 668

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

IS - 6

ER -

Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease

Abstract

Keywords

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