Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Bilateral diffuse uveal melanocytic proliferation: Case report and literature review

Research output: Contribution to journalReviewResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{9e927d9f10de49ad9828238ebdcbe114,
title = "Bilateral diffuse uveal melanocytic proliferation: Case report and literature review",
abstract = "Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic intraocular disease that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. Characteristic ocular findings include exudative retinal detachment, rapid cataract formation and uveal melanocytic tumours. The awareness and documentation of BDUMP has increased during the past decade, and the increasing amount of data collected demonstrates the effect of treatment with plasmapheresis and the value of diagnostic tools in BDUMP such as genetic and immunologic investigations. The literature of BDUMP has not been reviewed since 2003, and there is a growing need for an updated review on diagnosis and management of BDUMP. We review the literature and report a case of BDUMP with a white ciliary body tumour, iris rubeosis, increased iris pigmentation and cataract.",
keywords = "Aged, Cell Proliferation, Ciliary Body, Humans, Male, Melanocytes, Paraneoplastic Syndromes, Tomography, Optical Coherence, Uveal Diseases, Case Reports, Journal Article, Review",
author = "Kristian Klemp and Kiilgaard, {Jens Folke} and Steffen Heegaard and Tove N{\o}rgaard and Andersen, {Mette Klarskov} and Prause, {Jan Ulrik}",
note = "{\circledC} 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.",
year = "2017",
month = "8",
doi = "10.1111/aos.13481",
language = "English",
volume = "95",
pages = "439--445",
journal = "Acta Ophthalmologica",
issn = "1755-375X",
publisher = "Wiley-Blackwell Munksgaard",
number = "5",

}

RIS

TY - JOUR

T1 - Bilateral diffuse uveal melanocytic proliferation

T2 - Case report and literature review

AU - Klemp, Kristian

AU - Kiilgaard, Jens Folke

AU - Heegaard, Steffen

AU - Nørgaard, Tove

AU - Andersen, Mette Klarskov

AU - Prause, Jan Ulrik

N1 - © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

PY - 2017/8

Y1 - 2017/8

N2 - Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic intraocular disease that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. Characteristic ocular findings include exudative retinal detachment, rapid cataract formation and uveal melanocytic tumours. The awareness and documentation of BDUMP has increased during the past decade, and the increasing amount of data collected demonstrates the effect of treatment with plasmapheresis and the value of diagnostic tools in BDUMP such as genetic and immunologic investigations. The literature of BDUMP has not been reviewed since 2003, and there is a growing need for an updated review on diagnosis and management of BDUMP. We review the literature and report a case of BDUMP with a white ciliary body tumour, iris rubeosis, increased iris pigmentation and cataract.

AB - Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic intraocular disease that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. Characteristic ocular findings include exudative retinal detachment, rapid cataract formation and uveal melanocytic tumours. The awareness and documentation of BDUMP has increased during the past decade, and the increasing amount of data collected demonstrates the effect of treatment with plasmapheresis and the value of diagnostic tools in BDUMP such as genetic and immunologic investigations. The literature of BDUMP has not been reviewed since 2003, and there is a growing need for an updated review on diagnosis and management of BDUMP. We review the literature and report a case of BDUMP with a white ciliary body tumour, iris rubeosis, increased iris pigmentation and cataract.

KW - Aged

KW - Cell Proliferation

KW - Ciliary Body

KW - Humans

KW - Male

KW - Melanocytes

KW - Paraneoplastic Syndromes

KW - Tomography, Optical Coherence

KW - Uveal Diseases

KW - Case Reports

KW - Journal Article

KW - Review

U2 - 10.1111/aos.13481

DO - 10.1111/aos.13481

M3 - Review

VL - 95

SP - 439

EP - 445

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

SN - 1755-375X

IS - 5

ER -

ID: 52209321