Bias due to withdrawal in long-term randomised trials in COPD: evidence from the TORCH study

Jørgen Vestbo, Julie Anne Anderson, Peter Mark Anthony Calverley, Bartolomé Celli, Gary Thomas Ferguson, Christine Jenkins, Julie Carol Yates, Paul Wyatt Jones

71 Citations (Scopus)

Abstract

Randomised controlled trials (RCTs) are considered the least biased method for evaluating drug efficacy and several large long-term RCTs in chronic obstructive pulmonary disease have been published. These usually include drugs with symptomatic benefits and have significant withdrawal rates.
Original languageEnglish
JournalClinical Respiratory Journal
Volume5
Issue number1
Pages (from-to)44-9
Number of pages6
ISSN1752-6981
DOIs
Publication statusPublished - 2011

Keywords

  • Albuterol
  • Androstadienes
  • Bias (Epidemiology)
  • Bronchodilator Agents
  • Drug Combinations
  • Humans
  • Observation
  • Patient Dropouts
  • Placebos
  • Proportional Hazards Models
  • Pulmonary Disease, Chronic Obstructive
  • Randomized Controlled Trials as Topic

Fingerprint

Dive into the research topics of 'Bias due to withdrawal in long-term randomised trials in COPD: evidence from the TORCH study'. Together they form a unique fingerprint.

Cite this