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Bevacizumab in combination with cetuximab and irinotecan after failure of cetuximab and irinotecan in patients with metastatic colorectal cancer

Finn Ole Larsen, Per Pfeiffer, Dorte Nielsen, Kristin Skougaard, Camilla Qvortrup, Kirsten Vistisen, Anna-Lene Gunge Fromm, Trine Lembrecht Jørgensen, Jon Kroll Bjerregaard, Estrid Hoegdall, Benny V Jensen

13 Citations (Scopus)

Abstract

The efficacy and safety of concurrent administration of irinotecan with the two monoclonal antibodies cetuximab and bevacizumab as fourth line therapy in heavily pretreated patients with metastatic colorectal cancer were evaluated.
Original languageEnglish
JournalActa Oncologica
Volume50
Issue number4
Pages (from-to)574-7
Number of pages4
ISSN0284-186X
DOIs
Publication statusPublished - 2011

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Combined Chemotherapy Protocols
  • Camptothecin
  • Colorectal Neoplasms
  • Female
  • Humans
  • Liver Neoplasms
  • Male
  • Middle Aged
  • Mutation
  • Proto-Oncogene Proteins
  • Retrospective Studies
  • Survival Rate
  • Treatment Outcome
  • ras Proteins

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