Behandling af metforminassocieret laktatacidose med hæmodialyse

Karin Schousboe; Daniel El Fassi; Erik Lilja Secher; Hanne Elming; Knud Rasmussen; Mads Hornum

Behandling af metforminassocieret laktatacidose med hæmodialyse

Translated title of the contribution: Treatment of metformin-associated lactate acidosis by haemodialysis

Karin Schousboe, Daniel El Fassi, Erik Lilja Secher, Hanne Elming, Knud Rasmussen, Mads Hornum

4 Citations (Scopus)

Abstract

Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.

Translated title of the contribution	Treatment of metformin-associated lactate acidosis by haemodialysis
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	174
Issue number	23
Pages (from-to)	1604-6
Number of pages	3
ISSN	0041-5782
Publication status	Published - 2012

Cite this

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title = "Behandling af metforminassocieret laktatacidose med h{\ae}modialyse",

abstract = "Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.",

keywords = "Acidosis, Lactic, Aged, Diabetes Mellitus, Type 2, Female, Humans, Hypoglycemic Agents, Male, Metformin, Renal Dialysis",

author = "Karin Schousboe and {El Fassi}, Daniel and Secher, {Erik Lilja} and Hanne Elming and Knud Rasmussen and Mads Hornum",

year = "2012",

language = "Dansk",

volume = "174",

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journal = "Ugeskrift for Laeger",

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TY - JOUR

T1 - Behandling af metforminassocieret laktatacidose med hæmodialyse

AU - Schousboe, Karin

AU - El Fassi, Daniel

AU - Secher, Erik Lilja

AU - Elming, Hanne

AU - Rasmussen, Knud

AU - Hornum, Mads

PY - 2012

Y1 - 2012

N2 - Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.

AB - Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.

KW - Acidosis, Lactic

KW - Aged

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Humans

KW - Hypoglycemic Agents

KW - Male

KW - Metformin

KW - Renal Dialysis

M3 - Tidsskriftartikel

C2 - 22673381

SN - 0041-5782

VL - 174

SP - 1604

EP - 1606

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 23

ER -

Behandling af metforminassocieret laktatacidose med hæmodialyse

Abstract

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