Bacteriophages for the treatment of pseudomonas-infected vascular prosthesis

Andreas Ronit; Anders Porskrog; Sarah Djebara; Sigrid Bergmann; Jean-Paul Pirnay; Maia Merabishvili; Toke S Barfod; Kim Thomsen; Christian T Brandt

doi:10.61409/V09230617

Bacteriophages for the treatment of pseudomonas-infected vascular prosthesis

Translated title of the contribution: Not Available

Andreas Ronit, Anders Porskrog, Sarah Djebara, Sigrid Bergmann, Jean-Paul Pirnay, Maia Merabishvili, Toke S Barfod, Kim Thomsen, Christian T Brandt

Department of Infectious Diseases

1 Citation (Scopus)

Abstract

We present a case report detailing therapeutic application of two lytic antipseudomonal bacteriophages to treat a chronic relapsing Pseudomonas aeruginosa infection of a prosthetic aortic graft. As there are currently no Danish laboratories offering phages for clinical therapy, and this case, to our knowledge represents the first applied phage therapy in Denmark, the practical and regulatory aspects of offering this treatment option in Denmark is briefly reviewed along with the clinical case.

Translated title of the contribution	Not Available
Original language	Danish
Article number	V09230617
Journal	Ugeskrift for Laeger
Volume	186
Issue number	3
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V09230617
Publication status	Published - 22 Jan 2024

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10.61409/V09230617

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title = "Bacteriophages for the treatment of pseudomonas-infected vascular prosthesis",

abstract = "We present a case report detailing therapeutic application of two lytic antipseudomonal bacteriophages to treat a chronic relapsing Pseudomonas aeruginosa infection of a prosthetic aortic graft. As there are currently no Danish laboratories offering phages for clinical therapy, and this case, to our knowledge represents the first applied phage therapy in Denmark, the practical and regulatory aspects of offering this treatment option in Denmark is briefly reviewed along with the clinical case.",

keywords = "Humans, Bacteriophages, Pseudomonas, Pseudomonas Phages, Blood Vessel Prosthesis, Pseudomonas aeruginosa",

author = "Andreas Ronit and Anders Porskrog and Sarah Djebara and Sigrid Bergmann and Jean-Paul Pirnay and Maia Merabishvili and Barfod, \{Toke S\} and Kim Thomsen and Brandt, \{Christian T\}",

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T1 - Bacteriophages for the treatment of pseudomonas-infected vascular prosthesis

AU - Ronit, Andreas

AU - Porskrog, Anders

AU - Djebara, Sarah

AU - Bergmann, Sigrid

AU - Pirnay, Jean-Paul

AU - Merabishvili, Maia

AU - Barfod, Toke S

AU - Thomsen, Kim

AU - Brandt, Christian T

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2024/1/22

Y1 - 2024/1/22

N2 - We present a case report detailing therapeutic application of two lytic antipseudomonal bacteriophages to treat a chronic relapsing Pseudomonas aeruginosa infection of a prosthetic aortic graft. As there are currently no Danish laboratories offering phages for clinical therapy, and this case, to our knowledge represents the first applied phage therapy in Denmark, the practical and regulatory aspects of offering this treatment option in Denmark is briefly reviewed along with the clinical case.

AB - We present a case report detailing therapeutic application of two lytic antipseudomonal bacteriophages to treat a chronic relapsing Pseudomonas aeruginosa infection of a prosthetic aortic graft. As there are currently no Danish laboratories offering phages for clinical therapy, and this case, to our knowledge represents the first applied phage therapy in Denmark, the practical and regulatory aspects of offering this treatment option in Denmark is briefly reviewed along with the clinical case.

KW - Humans

KW - Bacteriophages

KW - Pseudomonas

KW - Pseudomonas Phages

KW - Blood Vessel Prosthesis

KW - Pseudomonas aeruginosa

UR - https://www.scopus.com/pages/publications/85184345543

U2 - 10.61409/V09230617

DO - 10.61409/V09230617

M3 - Tidsskriftartikel

C2 - 38305316

SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 3

M1 - V09230617

ER -

Bacteriophages for the treatment of pseudomonas-infected vascular prosthesis

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