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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial

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  • Viviana Galimberti
  • Bernard F Cole
  • Stefano Zurrida
  • Giuseppe Viale
  • Alberto Luini
  • Paolo Veronesi
  • Paola Baratella
  • Camelia Chifu
  • Manuela Sargenti
  • Mattia Intra
  • Oreste Gentilini
  • Mauro G Mastropasqua
  • Giovanni Mazzarol
  • Samuele Massarut
  • Jean-Rémi Garbay
  • Janez Zgajnar
  • Hanne Galatius
  • Angelo Recalcati
  • David Littlejohn
  • Monika Bamert
  • Marco Colleoni
  • Karen N Price
  • Meredith M Regan
  • Aron Goldhirsch
  • Alan S Coates
  • Richard D Gelber
  • Umberto Veronesi
  • International Breast Cancer Study Group Trial 23-01 investigators
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For patients with breast cancer and metastases in the sentinel nodes, axillary dissection has been standard treatment. However, for patients with limited sentinel-node involvement, axillary dissection might be overtreatment. We designed IBCSG trial 23-01 to determine whether no axillary dissection was non-inferior to axillary dissection in patients with one or more micrometastatic (≤2 mm) sentinel nodes and tumour of maximum 5 cm.
Original languageEnglish
JournalThe Lancet Oncology
Volume14
Issue number4
Pages (from-to)297-305
Number of pages9
ISSN1470-2045
DOIs
Publication statusPublished - Apr 2013

    Research areas

  • Adult, Aged, Axilla, Breast Neoplasms, Disease-Free Survival, Female, Follow-Up Studies, Humans, Lymph Nodes, Lymphatic Metastasis, Middle Aged, Neoplasm Grading, Neoplasm Micrometastasis, Sentinel Lymph Node Biopsy, Treatment Outcome

ID: 39767832