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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Autoantibodies and immunoglobulins in alcoholic steatosis and cirrhosis

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  1. Thyroid hormones and thyroxine-binding globulin in relation to liver function and serum testosterone in men with alcoholic cirrhosis

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  2. Increased plasma fibronectin concentrations in obesity: normalization during weight loss

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  3. Home readings of blood pressure in assessment of hypertensive subjects

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  4. The influence of insulin on the raised plasma fibronectin concentration in human obesity

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  5. Metabolic responses to hypoglycemia in juvenile diabetics

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  1. Acupuncture for chronic hepatitis B

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  2. Exercise-Based Rehabilitation for Heart Failure: Cochrane Systematic Review, Meta-Analysis, and Trial Sequential Analysis

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  3. Plasma expanders for people with cirrhosis and large ascites treated with abdominal paracentesis

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  4. Radix Sophorae flavescentis versus other drugs or herbs for chronic hepatitis B

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  5. Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

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Antinuclear antibodies were significantly more prevalent (p less than 0.01) in 143 patients with alcoholic cirrhosis than in 64 patients with alcoholic steatosis and in 94 controls. Smooth muscle antibodies were significantly more prevalent (p less than 0.05) in patients with alcoholic steatosis and cirrhosis than in controls. The prevalence of antimitochondrial antibodies and IgG liver membrane antibodies did not differ significantly between the three groups. Immunoglobulin G, A, and M concentrations were only occasionally increased in patients with steatosis. Patients with cirrhosis had significantly increased (p less than 0.005) concentrations of immunoglobulins G, A, and M when compared to patients with steatosis. These results indicate that the degree of liver damage has more effect than chronic alcoholism on the humoral immune system. Whether this influence is direct or indirect remains to be established.
Original languageEnglish
JournalActa medica Scandinavica. Supplementum
Volume214
Issue number1
Pages (from-to)61-6
Number of pages6
ISSN0365-463X
Publication statusPublished - 1983

    Research areas

  • Adult, Aged, Alcoholism, Antibodies, Antinuclear, Celiac Disease, Female, Humans, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, Immunoglobulins, Liver Cirrhosis, Alcoholic, Male, Middle Aged, Muscle, Smooth

ID: 38931359