Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Attenuated purinergic receptor function in patients with type 2 diabetes

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{bc99f95abcb84d5aac18fae25a1d78c5,
title = "Attenuated purinergic receptor function in patients with type 2 diabetes",
abstract = "Extracellular nucleotides and nucleosides are involved in regulation of skeletal muscle blood flow. Diabetes induces cardiovascular dysregulation, but the extent to which the vasodilatatory capacity of nucleotides and nucleosides is affected in type 2 diabetes is unknown. The present study investigated 1) the vasodilatatory effect of ATP, uridine-triphosphate (UTP), and adenosine (ADO) and 2) the expression and distribution of P2Y(2) and P2X(1) receptors in skeletal muscles of diabetic subjects.",
author = "Pia Thaning and Bune, {Laurids T} and Ylva Hellsten and Henriette Pilegaard and Bengt Saltin and Rosenmeier, {Jaya B}",
year = "2010",
month = "1",
day = "1",
doi = "10.2337/db09-1068",
language = "English",
volume = "59",
pages = "182--9",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "1",

}

RIS

TY - JOUR

T1 - Attenuated purinergic receptor function in patients with type 2 diabetes

AU - Thaning, Pia

AU - Bune, Laurids T

AU - Hellsten, Ylva

AU - Pilegaard, Henriette

AU - Saltin, Bengt

AU - Rosenmeier, Jaya B

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Extracellular nucleotides and nucleosides are involved in regulation of skeletal muscle blood flow. Diabetes induces cardiovascular dysregulation, but the extent to which the vasodilatatory capacity of nucleotides and nucleosides is affected in type 2 diabetes is unknown. The present study investigated 1) the vasodilatatory effect of ATP, uridine-triphosphate (UTP), and adenosine (ADO) and 2) the expression and distribution of P2Y(2) and P2X(1) receptors in skeletal muscles of diabetic subjects.

AB - Extracellular nucleotides and nucleosides are involved in regulation of skeletal muscle blood flow. Diabetes induces cardiovascular dysregulation, but the extent to which the vasodilatatory capacity of nucleotides and nucleosides is affected in type 2 diabetes is unknown. The present study investigated 1) the vasodilatatory effect of ATP, uridine-triphosphate (UTP), and adenosine (ADO) and 2) the expression and distribution of P2Y(2) and P2X(1) receptors in skeletal muscles of diabetic subjects.

U2 - 10.2337/db09-1068

DO - 10.2337/db09-1068

M3 - Journal article

VL - 59

SP - 182

EP - 189

JO - Diabetes

JF - Diabetes

SN - 0012-1797

IS - 1

ER -

ID: 32249418