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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Attenuated purinergic receptor function in patients with type 2 diabetes

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  1. Circulating Metabolites and Lipids Are Associated to Diabetic Retinopathy in Individuals With Type 1 Diabetes

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  2. GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in Hepatocyte Nuclear Factor 1-Alpha Mutation Carriers

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  3. Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects with Hepatic Steatosis

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  4. Epigenome-wide association study of incident type 2 diabetes in a British population: EPIC-Norfolk study

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Extracellular nucleotides and nucleosides are involved in regulation of skeletal muscle blood flow. Diabetes induces cardiovascular dysregulation, but the extent to which the vasodilatatory capacity of nucleotides and nucleosides is affected in type 2 diabetes is unknown. The present study investigated 1) the vasodilatatory effect of ATP, uridine-triphosphate (UTP), and adenosine (ADO) and 2) the expression and distribution of P2Y(2) and P2X(1) receptors in skeletal muscles of diabetic subjects.
Original languageEnglish
JournalDiabetes
Volume59
Issue number1
Pages (from-to)182-9
Number of pages8
DOIs
Publication statusPublished - 1 Jan 2010

ID: 32249418