Abstract
From mainly carcinoma cell line studies, apoptosis has been thought to play a major role in the pathogenesis of ulcerative colitis (UC). Apoptosis has been suggested to be due to a Fas ligand / Fas receptor interaction, but has never been studied in cells from patients with active UC. The aim was to investigate both the spontaneous and the cell death receptor ligand-induced apoptosis in UC.
| Original language | English |
|---|---|
| Journal | Inflammatory Bowel Diseases |
| Volume | 14 |
| Issue number | 12 |
| Pages (from-to) | 1623-9 |
| Number of pages | 7 |
| ISSN | 1078-0998 |
| DOIs | |
| Publication status | Published - 2008 |
Keywords
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antigens, CD95
- Antiviral Agents
- Apoptosis
- Case-Control Studies
- Cells, Cultured
- Colitis, Ulcerative
- Colon
- Fas Ligand Protein
- Female
- Flow Cytometry
- Fluorescent Antibody Technique
- HT29 Cells
- Humans
- Interferon-gamma
- Male
- Middle Aged
- Young Adult
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