TY - JOUR
T1 - Asthma in elite athletes - do they have Type 2 or non-Type 2 disease?
T2 - A new insight on the endotypes among elite athletes
AU - Rasmussen, Søren Malte
AU - Hansen, Erik Sören Halvard
AU - Backer, Vibeke
N1 - © 2022 Rasmussen, Hansen and Backer.
PY - 2022
Y1 - 2022
N2 - Asthma and exercise-induced bronchoconstriction are highly prevalent in elite athletes compared with the general population. Some athletes have classic asthma with allergic sensitization; however, it seems that a proportion of athletes develop asthma as a result of several years of intensive training. It leads us to believe that asthma in athletes consists of at least two distinct endotypes - classic early-onset, Type 2 mediated asthma, and asthma with later onset caused by exercise which might be classified as non-Type 2 asthma. The purpose of this review is to evaluate the current literature on asthma in athletes focusing on inflammation and examine if asthma in athletes could be characterized as either Type 2- or non-Type 2 asthma.
AB - Asthma and exercise-induced bronchoconstriction are highly prevalent in elite athletes compared with the general population. Some athletes have classic asthma with allergic sensitization; however, it seems that a proportion of athletes develop asthma as a result of several years of intensive training. It leads us to believe that asthma in athletes consists of at least two distinct endotypes - classic early-onset, Type 2 mediated asthma, and asthma with later onset caused by exercise which might be classified as non-Type 2 asthma. The purpose of this review is to evaluate the current literature on asthma in athletes focusing on inflammation and examine if asthma in athletes could be characterized as either Type 2- or non-Type 2 asthma.
U2 - 10.3389/falgy.2022.973004
DO - 10.3389/falgy.2022.973004
M3 - Review
C2 - 36340019
SN - 2673-6101
VL - 3
SP - 973004
JO - Frontiers in allergy
JF - Frontiers in allergy
ER -