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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Associations of Filaggrin Gene Loss-of-Function Variants with Urinary Phthalate Metabolites and Testicular Function in Young Danish Men

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  1. Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort

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  2. Long-Term Exposure to Air Pollution and Incidence of Myocardial Infarction: A Danish Nurse Cohort Study

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  3. Long-Term Exposure to Road Traffic Noise and Incidence of Diabetes in the Danish Nurse Cohort

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  1. Associations of serum phthalate metabolites with thyroid hormones in GraMo cohort, Southern Spain

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  2. Incidence rates of occupational contact dermatitis in Denmark between 2007 and 2018 - A population-based study

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  3. Thyroid function in COVID-19 and the association with cytokine levels and mortality

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  4. The effects of selected inhibitors on human fetal adrenal steroidogenesis differs under basal and ACTH-stimulated conditions

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  5. Cohort profile: The COPENHAGEN Minipuberty Study-A longitudinal prospective cohort of healthy full-term infants and their parents

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Filaggrin is an epidermal protein that is crucial for skin barrier function. Up to 10% of Europeans and 5% of Asians carry at least one null allele in the filaggrin gene (FLG). Reduced expression of filaggrin in null allele carriers is associated with facilitated transfer of allergens across the epidermis. We hypothesized that these individuals may have increased transdermal uptake of endocrine disruptors, including phthalates.
Original languageEnglish
JournalEnvironmental Health Perspectives
Volume122
Issue number4
Pages (from-to)345-350
Number of pages5
ISSN0091-6765
DOIs
Publication statusPublished - Apr 2014

ID: 42352921