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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Associations of Filaggrin Gene Loss-of-Function Variants with Urinary Phthalate Metabolites and Testicular Function in Young Danish Men

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  1. Long-Term Exposure to Road Traffic Noise and Incidence of Diabetes in the Danish Nurse Cohort

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  2. Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study

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  1. Allergic contact stomatitis caused by (meth)acrylates in an occlusal splint

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  2. Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

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  3. Exposure analysis using X-ray fluorescence device and a cobalt spot test in four patients with cobalt allergy

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  4. Adipose tissue concentrations of non-persistent environmental phenols and local redox balance in adults from Southern Spain

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Filaggrin is an epidermal protein that is crucial for skin barrier function. Up to 10% of Europeans and 5% of Asians carry at least one null allele in the filaggrin gene (FLG). Reduced expression of filaggrin in null allele carriers is associated with facilitated transfer of allergens across the epidermis. We hypothesized that these individuals may have increased transdermal uptake of endocrine disruptors, including phthalates.
Original languageEnglish
JournalEnvironmental Health Perspectives
Volume122
Issue number4
Pages (from-to)345-350
Number of pages5
ISSN0091-6765
DOIs
Publication statusPublished - Apr 2014

ID: 42352921