Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes

Charlotte Andersson; Stig Lyngbæk; Cu Dinh Nguyen; Mia Nielsen; Gunnar H Gislason; Lars Køber; Christian Torp-Pedersen

doi:10.1001/2012.jama.10779

Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes

Charlotte Andersson, Stig Lyngbæk, Cu Dinh Nguyen, Mia Nielsen, Gunnar H Gislason, Lars Køber, Christian Torp-Pedersen

45 Citations (Scopus)

Abstract

Pharmacodynamic studies have shown that persistently high platelet reactivity is common in patients with diabetes in spite of clopidogrel treatment. Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes.

Original language	English
Journal	J A M A: The Journal of the American Medical Association
Volume	308
Issue number	9
Pages (from-to)	882-9
Number of pages	8
ISSN	0098-7484
DOIs	https://doi.org/10.1001/2012.jama.10779
Publication status	Published - 2012

Keywords

Aged
Aged, 80 and over
Cardiovascular Diseases
Case-Control Studies
Data Collection
Denmark
Diabetes Mellitus
Female
Humans
Male
Middle Aged
Mortality
Myocardial Infarction
Platelet Activation
Platelet Aggregation Inhibitors
Registries
Risk
Ticlopidine

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10.1001/2012.jama.10779

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Andersson, C., Lyngbæk, S., Nguyen, C. D., Nielsen, M., Gislason, G. H., Køber, L., & Torp-Pedersen, C. (2012). Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes. J A M A: The Journal of the American Medical Association, 308(9), 882-9. https://doi.org/10.1001/2012.jama.10779

Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes. / Andersson, Charlotte; Lyngbæk, Stig; Nguyen, Cu Dinh et al.
In: J A M A: The Journal of the American Medical Association, Vol. 308, No. 9, 2012, p. 882-9.

Research output: Contribution to journal › Journal article › Research › peer-review

Andersson, C, Lyngbæk, S, Nguyen, CD, Nielsen, M, Gislason, GH , Køber, L & Torp-Pedersen, C 2012, 'Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes', J A M A: The Journal of the American Medical Association, vol. 308, no. 9, pp. 882-9. https://doi.org/10.1001/2012.jama.10779

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keywords = "Aged, Aged, 80 and over, Cardiovascular Diseases, Case-Control Studies, Data Collection, Denmark, Diabetes Mellitus, Female, Humans, Male, Middle Aged, Mortality, Myocardial Infarction, Platelet Activation, Platelet Aggregation Inhibitors, Registries, Risk, Ticlopidine",

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AU - Nielsen, Mia

AU - Gislason, Gunnar H

AU - Køber, Lars

AU - Torp-Pedersen, Christian

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Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes

Abstract

Keywords

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