Association between refill compliance to oral bisphosphonate treatment, incident fractures, and health care costs--an analysis using national health databases

K R Olsen, C Hansen, B Abrahamsen

    30 Citations (Scopus)

    Abstract

    The study estimates the cost of poor and suboptimal refill compliance by estimating fracture costs and assessing the association between refill compliance with oral bisphosphonates and incident fractures using Danish health registers. Patients with poor and suboptimal refill compliance had more major osteoporotic fractures, and the direct costs related to hospital care, primary care, and pharmaceutical treatment for these excess fractures reached almost 14 M DKK (2.5 M USD) for the study population which compares to a national annual excess cost of around 17 M DKK (3.1 M USD) using 2011 prescription prevalence.
    Original languageEnglish
    JournalOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
    Volume24
    Issue number10
    Pages (from-to)2639-47
    Number of pages9
    ISSN0937-941X
    DOIs
    Publication statusPublished - Oct 2013

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