Association between objectively measured sleep duration, adiposity and weight loss history

Sofus C Larsen; Graham Horgan; Marie-Louise K Mikkelsen; Antonio L Palmeira; Sarah Scott; Cristiana Duarte; Inês Santos; Jorge Encantado; Ruairi O' Driscoll; Jake Turicchi; Joanna Michalowska; James Stubbs; Berit L Heitmann

doi:10.1038/s41366-020-0537-3

Association between objectively measured sleep duration, adiposity and weight loss history

Sofus C Larsen, Graham Horgan, Marie-Louise K Mikkelsen, Antonio L Palmeira, Sarah Scott, Cristiana Duarte, Inês Santos, Jorge Encantado, Ruairi O' Driscoll, Jake Turicchi, Joanna Michalowska, James Stubbs, Berit L Heitmann

The Parker Institute

16 Citations (Scopus)

Abstract

BACKGROUND: An association between sleep and obesity has been suggested in several studies, but many previous studies relied on self-reported sleep and on BMI as the only adiposity measure. Moreover, a relationship between weight loss history and attained sleep duration has not been thoroughly explored.

DESIGN: The study comprised of 1202 participants of the European NoHoW trial who had achieved a weight loss of ≥5% and had a BMI of ≥25 kg/m2 prior to losing weight. Information was available on objectively measured sleep duration (collected during 14 days), adiposity measures, weight loss history and covariates. Regression models were conducted with sleep duration as the explanatory variable and BMI, fat mass index (FMI), fat-free mass index (FFMI) and waist-hip ratio (WHR) as response variables. Analyses were conducted with 12-month weight loss, frequency of prior weight loss attempts or average duration of weight maintenance after prior weight loss attempts as predictors of measured sleep duration.

RESULTS: After adjusting for physical activity, perceived stress, smoking, alcohol consumption, education, sex and age, sleep duration was associated to BMI (P < 0.001), with the highest BMI observed in the group of participants sleeping <6 h a day [34.0 kg/m2 (95% CI: 31.8-36.1)]. Less difference in BMI was detected between the remaining groups, with the lowest BMI observed among participants sleeping 8-<9 h a day [29.4 kg/m2 (95% CI: 28.8-29.9)]. Similar results were found for FMI (P = 0.008) and FFMI (P < 0.001). We found no association between sleep duration and WHR. Likewise, we found no associations between weight loss history and attained sleep duration.

CONCLUSION: In an overweight population who had achieved a clinically significant weight loss, short sleep duration was associated with higher BMI, with similar associations for fat and lean mass. We found no evidence of association between weight loss history and attained sleep duration.

Original language	English
Journal	International journal of obesity (2005)
Volume	44
Issue number	7
Pages (from-to)	1577-1585
Number of pages	9
ISSN	0307-0565
DOIs	https://doi.org/10.1038/s41366-020-0537-3
Publication status	Published - Jul 2020

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Larsen, S. C., Horgan, G., Mikkelsen, M.-L. K., Palmeira, A. L., Scott, S., Duarte, C., Santos, I., Encantado, J., Driscoll, R. O., Turicchi, J., Michalowska, J., Stubbs, J., & Heitmann, B. L. (2020). Association between objectively measured sleep duration, adiposity and weight loss history. International journal of obesity (2005), 44(7), 1577-1585. https://doi.org/10.1038/s41366-020-0537-3

Larsen, SC, Horgan, G, Mikkelsen, M-LK, Palmeira, AL, Scott, S, Duarte, C, Santos, I, Encantado, J, Driscoll, RO, Turicchi, J, Michalowska, J, Stubbs, J & Heitmann, BL 2020, 'Association between objectively measured sleep duration, adiposity and weight loss history', International journal of obesity (2005), vol. 44, no. 7, pp. 1577-1585. https://doi.org/10.1038/s41366-020-0537-3

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title = "Association between objectively measured sleep duration, adiposity and weight loss history",

abstract = "BACKGROUND: An association between sleep and obesity has been suggested in several studies, but many previous studies relied on self-reported sleep and on BMI as the only adiposity measure. Moreover, a relationship between weight loss history and attained sleep duration has not been thoroughly explored.DESIGN: The study comprised of 1202 participants of the European NoHoW trial who had achieved a weight loss of ≥5\% and had a BMI of ≥25 kg/m2 prior to losing weight. Information was available on objectively measured sleep duration (collected during 14 days), adiposity measures, weight loss history and covariates. Regression models were conducted with sleep duration as the explanatory variable and BMI, fat mass index (FMI), fat-free mass index (FFMI) and waist-hip ratio (WHR) as response variables. Analyses were conducted with 12-month weight loss, frequency of prior weight loss attempts or average duration of weight maintenance after prior weight loss attempts as predictors of measured sleep duration.RESULTS: After adjusting for physical activity, perceived stress, smoking, alcohol consumption, education, sex and age, sleep duration was associated to BMI (P < 0.001), with the highest BMI observed in the group of participants sleeping <6 h a day [34.0 kg/m2 (95\% CI: 31.8-36.1)]. Less difference in BMI was detected between the remaining groups, with the lowest BMI observed among participants sleeping 8-<9 h a day [29.4 kg/m2 (95\% CI: 28.8-29.9)]. Similar results were found for FMI (P = 0.008) and FFMI (P < 0.001). We found no association between sleep duration and WHR. Likewise, we found no associations between weight loss history and attained sleep duration.CONCLUSION: In an overweight population who had achieved a clinically significant weight loss, short sleep duration was associated with higher BMI, with similar associations for fat and lean mass. We found no evidence of association between weight loss history and attained sleep duration.",

author = "Larsen, \{Sofus C\} and Graham Horgan and Mikkelsen, \{Marie-Louise K\} and Palmeira, \{Antonio L\} and Sarah Scott and Cristiana Duarte and In{\^e}s Santos and Jorge Encantado and Driscoll, \{Ruairi O'\} and Jake Turicchi and Joanna Michalowska and James Stubbs and Heitmann, \{Berit L\}",

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doi = "10.1038/s41366-020-0537-3",

language = "English",

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pages = "1577--1585",

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T1 - Association between objectively measured sleep duration, adiposity and weight loss history

AU - Larsen, Sofus C

AU - Horgan, Graham

AU - Mikkelsen, Marie-Louise K

AU - Palmeira, Antonio L

AU - Scott, Sarah

AU - Duarte, Cristiana

AU - Santos, Inês

AU - Encantado, Jorge

AU - Driscoll, Ruairi O'

AU - Turicchi, Jake

AU - Michalowska, Joanna

AU - Stubbs, James

AU - Heitmann, Berit L

PY - 2020/7

Y1 - 2020/7

N2 - BACKGROUND: An association between sleep and obesity has been suggested in several studies, but many previous studies relied on self-reported sleep and on BMI as the only adiposity measure. Moreover, a relationship between weight loss history and attained sleep duration has not been thoroughly explored.DESIGN: The study comprised of 1202 participants of the European NoHoW trial who had achieved a weight loss of ≥5% and had a BMI of ≥25 kg/m2 prior to losing weight. Information was available on objectively measured sleep duration (collected during 14 days), adiposity measures, weight loss history and covariates. Regression models were conducted with sleep duration as the explanatory variable and BMI, fat mass index (FMI), fat-free mass index (FFMI) and waist-hip ratio (WHR) as response variables. Analyses were conducted with 12-month weight loss, frequency of prior weight loss attempts or average duration of weight maintenance after prior weight loss attempts as predictors of measured sleep duration.RESULTS: After adjusting for physical activity, perceived stress, smoking, alcohol consumption, education, sex and age, sleep duration was associated to BMI (P < 0.001), with the highest BMI observed in the group of participants sleeping <6 h a day [34.0 kg/m2 (95% CI: 31.8-36.1)]. Less difference in BMI was detected between the remaining groups, with the lowest BMI observed among participants sleeping 8-<9 h a day [29.4 kg/m2 (95% CI: 28.8-29.9)]. Similar results were found for FMI (P = 0.008) and FFMI (P < 0.001). We found no association between sleep duration and WHR. Likewise, we found no associations between weight loss history and attained sleep duration.CONCLUSION: In an overweight population who had achieved a clinically significant weight loss, short sleep duration was associated with higher BMI, with similar associations for fat and lean mass. We found no evidence of association between weight loss history and attained sleep duration.

AB - BACKGROUND: An association between sleep and obesity has been suggested in several studies, but many previous studies relied on self-reported sleep and on BMI as the only adiposity measure. Moreover, a relationship between weight loss history and attained sleep duration has not been thoroughly explored.DESIGN: The study comprised of 1202 participants of the European NoHoW trial who had achieved a weight loss of ≥5% and had a BMI of ≥25 kg/m2 prior to losing weight. Information was available on objectively measured sleep duration (collected during 14 days), adiposity measures, weight loss history and covariates. Regression models were conducted with sleep duration as the explanatory variable and BMI, fat mass index (FMI), fat-free mass index (FFMI) and waist-hip ratio (WHR) as response variables. Analyses were conducted with 12-month weight loss, frequency of prior weight loss attempts or average duration of weight maintenance after prior weight loss attempts as predictors of measured sleep duration.RESULTS: After adjusting for physical activity, perceived stress, smoking, alcohol consumption, education, sex and age, sleep duration was associated to BMI (P < 0.001), with the highest BMI observed in the group of participants sleeping <6 h a day [34.0 kg/m2 (95% CI: 31.8-36.1)]. Less difference in BMI was detected between the remaining groups, with the lowest BMI observed among participants sleeping 8-<9 h a day [29.4 kg/m2 (95% CI: 28.8-29.9)]. Similar results were found for FMI (P = 0.008) and FFMI (P < 0.001). We found no association between sleep duration and WHR. Likewise, we found no associations between weight loss history and attained sleep duration.CONCLUSION: In an overweight population who had achieved a clinically significant weight loss, short sleep duration was associated with higher BMI, with similar associations for fat and lean mass. We found no evidence of association between weight loss history and attained sleep duration.

UR - https://www.scopus.com/pages/publications/85078022473

U2 - 10.1038/s41366-020-0537-3

DO - 10.1038/s41366-020-0537-3

M3 - Journal article

C2 - 31937906

SN - 0307-0565

VL - 44

SP - 1577

EP - 1585

JO - International journal of obesity (2005)

JF - International journal of obesity (2005)

IS - 7

ER -

Association between objectively measured sleep duration, adiposity and weight loss history

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