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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Association between lectin complement pathway initiators, C-reactive protein and left ventricular remodeling in myocardial infarction-a magnetic resonance study

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  1. Peripheral memory T cells specific for Arginase-1

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  2. Ficolin-2 reveals different analytical and biological properties dependent on different sample handling procedures

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  3. The role of ficolins and MASPs in hereditary angioedema due to C1-inhibitor deficiency

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  1. Pro-inflammatory biomarkers in women with non-obstructive angina pectoris and coronary microvascular dysfunction

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  2. Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)

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Lectin complement pathway (LP) activation is an important mechanism in myocardial ischemia reperfusion injury (IRI). LP is activated via the recognition molecules mannose-binding lectin (MBL), ficolins-2 and-3 and is regulated by MBL/Ficolin-associated Protein-1 (MAP-1). Also, C-reactive protein (CRP) and ficolin-2 interact in vitro, but the role of the ficolins in IRI is unknown.
Original languageEnglish
JournalCellular & Molecular Immunology
Volume54
Issue number3-4
Pages (from-to)408-14
Number of pages7
ISSN1672-7681
DOIs
Publication statusPublished - Jul 2013

    Research areas

  • Adaptor Proteins, Signal Transducing, Apoptosis Regulatory Proteins, C-Reactive Protein, Complement Pathway, Mannose-Binding Lectin, Double-Blind Method, Female, Follow-Up Studies, Glycoproteins, Humans, Lectins, Magnetic Resonance Imaging, Male, Mannose-Binding Lectins, Middle Aged, Myocardial Infarction, Prospective Studies, Randomized Controlled Trials as Topic, Retrospective Studies, Ventricular Remodeling

ID: 39017212