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Artifacts in conventional computed tomography (CT) and free breathing four-dimensional CT induce uncertainty in gross tumor volume determination

Gitte Fredberg Persson, Ditte Eklund Nygaard, Per Munck Af Rosenschöld, Ivan Richter Vogelius, Mirjana Josipovic, Lena Specht, Stine Sofia Korreman

    50 Citations (Scopus)

    Abstract

    Artifacts impacting the imaged tumor volume can be seen in conventional three-dimensional CT (3DCT) scans for planning of lung cancer radiotherapy but can be reduced with the use of respiration-correlated imaging, i.e., 4DCT or breathhold CT (BHCT) scans. The aim of this study was to compare delineated gross tumor volume (GTV) sizes in 3DCT, 4DCT, and BHCT scans of patients with lung tumors.
    Original languageEnglish
    JournalInternational Journal of Radiation: Oncology - Biology - Physics
    Volume80
    Issue number5
    Pages (from-to)1573-80
    Number of pages8
    ISSN0360-3016
    DOIs
    Publication statusPublished - 1 Aug 2011

    Keywords

    • Artifacts
    • Fiducial Markers
    • Four-Dimensional Computed Tomography
    • Humans
    • Lung Neoplasms
    • Movement
    • Positron-Emission Tomography
    • Reference Values
    • Respiration
    • Tomography, X-Ray Computed
    • Tumor Burden
    • Uncertainty

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