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Are marketed topical metronidazole creams bioequivalent? Evaluation by in vivo microdialysis sampling and tape stripping methodology

Patricia Elodia Garcia Ortiz, S H Hansen, Surendra P. Shah, J Sonne, Eva Merete Benfeldt

31 Citations (Scopus)

Abstract

To evaluate the bioequivalence of 3 marketed topical metronidazole formulations by simultaneous dermal microdialysis and stratum corneum sampling by the tape stripping methodology, and to compare the techniques as tools for the determination of bioequivalence.
Original languageEnglish
JournalSkin Pharmacology and Physiology (Print)
Volume24
Issue number1
Pages (from-to)44-53
Number of pages10
ISSN1660-5527
DOIs
Publication statusPublished - 1 Jan 2011

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