Are all melanomas dangerous?

Carsten Nørgaard, Martin Glud, Robert Gniadecki

24 Citations (Scopus)

Abstract

The increased incidence of cutaneous malignant melanoma, together with only minor changes in mortality, has brought into question the existence of a melanoma epidemic. The discrepancy between incidence and mortality suggests that most newly diagnosed melanomas have indolent behaviour. This review summarizes the most recent epidemiological findings regarding the incidence of cutaneous malignant melanoma, mortality, Breslow thickness and clinical stage. Studies published between 2005 and 2010 with more than 2,000 test subjects were included in this review. These studies all report an increase in incidence of melanoma during the last few decades, with by far the highest increase in tumours at a very early stage (T1 or IA). Little or no change was seen in mortality. However, increases in both mortality and incidence of thick melanomas were found in the oldest subgroups, especially in men. These findings indicate the existence of a certain degree of overdiagnosis of melanoma. They also indicate the existence of two different types of epidemic, for younger and older subgroups.
Original languageEnglish
JournalActa Dermato Venereologica
Volume91
Issue number5
Pages (from-to)499-503
Number of pages5
ISSN0001-5555
DOIs
Publication statusPublished - 2011

Keywords

  • Age Factors
  • Female
  • Humans
  • Incidence
  • Male
  • Melanoma
  • Neoplasm Staging
  • Predictive Value of Tests
  • Prognosis
  • Risk Assessment
  • Risk Factors
  • Sex Factors
  • Skin Neoplasms
  • Time Factors

Fingerprint

Dive into the research topics of 'Are all melanomas dangerous?'. Together they form a unique fingerprint.

Cite this