Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

Sara Elsøe; Christina Christoffersen; Jayraz Luchoomun; Scott Turner; Lars Bo Nielsen

doi:10.1016/j.bbalip.2013.04.009

Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

Sara Elsøe, Christina Christoffersen, Jayraz Luchoomun, Scott Turner, Lars Bo Nielsen

Department of Clinical Biochemistry

36 Citations (Scopus)

Abstract

The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.

Original language	English
Journal	Biochimica et Biophysica Acta
Volume	1831
Issue number	7
Pages (from-to)	1287-92
Number of pages	6
ISSN	0006-3002
DOIs	https://doi.org/10.1016/j.bbalip.2013.04.009
Publication status	Published - Jul 2013

Keywords

Animals
Apolipoproteins
Atherosclerosis
Bile
Cell Line
Cholesterol
Feces
Foam Cells
Gene Deletion
Humans
Lipid Metabolism
Lipoproteins, HDL
Macrophages
Mice
Mice, Inbred C57BL
Mice, Transgenic

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10.1016/j.bbalip.2013.04.009

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title = "Apolipoprotein M promotes mobilization of cellular cholesterol in vivo",

abstract = "The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.",

keywords = "Animals, Apolipoproteins, Atherosclerosis, Bile, Cell Line, Cholesterol, Feces, Foam Cells, Gene Deletion, Humans, Lipid Metabolism, Lipoproteins, HDL, Macrophages, Mice, Mice, Inbred C57BL, Mice, Transgenic",

author = "Sara Els{\o}e and Christina Christoffersen and Jayraz Luchoomun and Scott Turner and Nielsen, \{Lars Bo\}",

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journal = "Biochimica et Biophysica Acta",

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T1 - Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

AU - Elsøe, Sara

AU - Christoffersen, Christina

AU - Luchoomun, Jayraz

AU - Turner, Scott

AU - Nielsen, Lars Bo

PY - 2013/7

Y1 - 2013/7

N2 - The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.

AB - The HDL associated apolipoprotein M (apoM) protects against experimental atherosclerosis but the mechanism is unknown. ApoM increases prebeta-HDL formation. We explored whether plasma apoM affects mobilization of cholesterol from peripheral cells in mice.

KW - Animals

KW - Apolipoproteins

KW - Atherosclerosis

KW - Bile

KW - Cell Line

KW - Cholesterol

KW - Feces

KW - Foam Cells

KW - Gene Deletion

KW - Humans

KW - Lipid Metabolism

KW - Lipoproteins, HDL

KW - Macrophages

KW - Mice

KW - Mice, Inbred C57BL

KW - Mice, Transgenic

UR - https://www.scopus.com/pages/publications/84878422212

U2 - 10.1016/j.bbalip.2013.04.009

DO - 10.1016/j.bbalip.2013.04.009

M3 - Journal article

C2 - 24046869

SN - 0006-3002

VL - 1831

SP - 1287

EP - 1292

JO - Biochimica et Biophysica Acta

JF - Biochimica et Biophysica Acta

IS - 7

ER -

Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

Abstract

Keywords

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