Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program

Susan E Beekmann; Kris P Heilmann; Sandra S Richter; Juan García-de-Lomas; Gary V Doern; GRASP Study Group; Bettina Lundgren

doi:10.1016/j.ijantimicag.2004.09.016

Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program

Susan E Beekmann, Kris P Heilmann, Sandra S Richter, Juan García-de-Lomas, Gary V Doern, GRASP Study Group, Bettina Lundgren

101 Citations (Scopus)

Abstract

A multinational surveillance study, GRASP, was conducted between November 2002 and April 2003 with the aim of assessing rates of antimicrobial resistance among 2656 isolates of Streptococcus pneumoniae, 2486 isolates of group A beta-haemolytic streptococci, 1358 isolates of Haemophilus influenzae and 1047 of Moraxella catarrhalis from 20 countries in Europe, eastern Asia and southern Africa. Conspicuous differences between various countries were noted in the S. pneumoniae resistance rates observed for penicillin (0-79.2%) and erythromycin (4-66%), along with other antimicrobials. The percentage of MDR strains was above 25% in 8 of the 20 countries studied. Group A streptococcal macrolide resistance rates ranged from 0% to 35% by country, while rates of beta-lactamase production ranged from 0% to 39% for H. influenzae and 80-100% for M. catarrhalis. Antibiotic resistance in S. pneumoniae remains a significant problem world wide.

Original language	English
Journal	International Journal of Antimicrobial Agents
Volume	25
Issue number	2
Pages (from-to)	148-56
Number of pages	9
ISSN	0924-8579
DOIs	https://doi.org/10.1016/j.ijantimicag.2004.09.016
Publication status	Published - Feb 2005

Keywords

Adult
Anti-Bacterial Agents
Bacteria
Community-Acquired Infections
Drug Resistance, Bacterial
Haemophilus influenzae
Humans
Internationality
Microbial Sensitivity Tests
Middle Aged
Moraxella (Branhamella) catarrhalis
Population Surveillance
Respiratory Tract Infections
Streptococcus
Streptococcus pneumoniae
Streptococcus pyogenes

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Beekmann, S. E., Heilmann, K. P., Richter, S. S., García-de-Lomas, J., Doern, G. V., GRASP Study Group, & Lundgren, B. (2005). Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program. International Journal of Antimicrobial Agents, 25(2), 148-56. https://doi.org/10.1016/j.ijantimicag.2004.09.016

Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program. / Beekmann, Susan E; Heilmann, Kris P; Richter, Sandra S et al.
In: International Journal of Antimicrobial Agents, Vol. 25, No. 2, 02.2005, p. 148-56.

Research output: Contribution to journal › Journal article › Research › peer-review

Beekmann, SE, Heilmann, KP, Richter, SS, García-de-Lomas, J, Doern, GV, GRASP Study Group & Lundgren, B 2005, 'Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program', International Journal of Antimicrobial Agents, vol. 25, no. 2, pp. 148-56. https://doi.org/10.1016/j.ijantimicag.2004.09.016

Beekmann SE, Heilmann KP, Richter SS, García-de-Lomas J, Doern GV, GRASP Study Group et al. Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program. International Journal of Antimicrobial Agents. 2005 Feb;25(2):148-56. doi: 10.1016/j.ijantimicag.2004.09.016

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abstract = "A multinational surveillance study, GRASP, was conducted between November 2002 and April 2003 with the aim of assessing rates of antimicrobial resistance among 2656 isolates of Streptococcus pneumoniae, 2486 isolates of group A beta-haemolytic streptococci, 1358 isolates of Haemophilus influenzae and 1047 of Moraxella catarrhalis from 20 countries in Europe, eastern Asia and southern Africa. Conspicuous differences between various countries were noted in the S. pneumoniae resistance rates observed for penicillin (0-79.2\%) and erythromycin (4-66\%), along with other antimicrobials. The percentage of MDR strains was above 25\% in 8 of the 20 countries studied. Group A streptococcal macrolide resistance rates ranged from 0\% to 35\% by country, while rates of beta-lactamase production ranged from 0\% to 39\% for H. influenzae and 80-100\% for M. catarrhalis. Antibiotic resistance in S. pneumoniae remains a significant problem world wide.",

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AU - Heilmann, Kris P

AU - Richter, Sandra S

AU - García-de-Lomas, Juan

AU - Doern, Gary V

AU - GRASP Study Group

AU - Lundgren, Bettina

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KW - Middle Aged

KW - Moraxella (Branhamella) catarrhalis

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KW - Respiratory Tract Infections

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KW - Streptococcus pyogenes

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Antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and group A beta-haemolytic streptococci in 2002-2003. Results of the multinational GRASP Surveillance Program

Abstract

Keywords

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