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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Antibiofilm Properties of Acetic Acid

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DOI

  1. An Equine Wound Model to Study Effects of Bacterial Aggregates on Wound Healing

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  2. Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds

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  1. Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model

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  2. The Extracellular Polysaccharide Matrix of Pseudomonas aeruginosa Biofilms Is a Determinant of Polymorphonuclear Leukocyte Responses

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  3. Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

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  4. Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

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Bacterial biofilms are known to be extremely tolerant toward antibiotics and other antimicrobial agents. These biofilms cause the persistence of chronic infections. Since antibiotics rarely resolve these infections, the only effective treatment of chronic infections is surgical removal of the infected implant, tissue, or organ and thereby the biofilm. Acetic acid is known for its antimicrobial effect on bacteria in general, but has never been thoroughly tested for its efficacy against bacterial biofilms. In this article, we describe complete eradication of both Gram-positive and Gram-negative biofilms using acetic acid both as a liquid and as a dry salt. In addition, we present our clinical experience of acetic acid treatment of chronic wounds. In conclusion, we here present the first comprehensive in vitro and in vivo testing of acetic acid against bacterial biofilms.

Original languageEnglish
JournalAdvances in Wound Care
Volume4
Issue number7
Pages (from-to)363-372
Number of pages10
ISSN2162-1918
DOIs
Publication statusPublished - 1 Jul 2015

ID: 45583404