Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Anatomical challenges for transcatheter mitral valve intervention

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Is EVAR a durable solution? Indications for reinterventions

    Research output: Contribution to journalReviewResearchpeer-review

  2. Expanding the indications for transcatheter aortic valve implantation: is it time to treat low risk patients?

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The management of ruptured abdominal aortic aneurysms

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Influence of gender on EVAR outcomes with new low-profile devices

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Are there fewer complications with third generation endografts in endovascular aneurysm repair?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. First-in-human results of the OMEGA™ Left Atrial Appendage Occluder for Patients with Non-Valvular Atrial Fibrillation

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Impact of early hospital discharge on clinical outcomes after transcatheter aortic valve implantation

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Infective Endocarditis Following Transcatheter Aortic Valve Replacement and Cardiac Implantable Electronic Device

    Research output: Contribution to journalLetterResearchpeer-review

  4. Contemporary management of severe symptomatic bicuspid aortic valve stenosis: the BiTri Registry

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Following the success of transcatheter aortic and pulmonary valve implantation, there is a large interest in transcatheter mitral valve interventions to treat severe mitral regurgitation (MR). With the exception for the MitraClip™ (Abbott, Abbott Park, IL, USA) edge-to-edge leaflet plication system, most of these transcatheter mitral valve interventions are still in their early clinical or preclinical development phase. Challenges arising from the complex anatomy of the mitral valve and the interplay of the mitral apparatus with the left ventricle (LV) have contributed to a more difficult development process and mixed clinical results with these novel technologies. This review aims to discuss the several anatomical aspects and challenges related to transcatheter mitral valve intervention--the relevant anatomy will be reviewed in relation to specific requirements for device design and procedural aspects of transcatheter mitral valve interventions. To date, experience with these novel therapeutic modalities are still limited and resolution of many challenges are pending. Future studies have to evaluate for whom the transcatheter approach is a feasible and preferred treatment and which patients will benefit from either transcatheter mitral valve repair or replacement. Nevertheless, technological developments are anticipated to drive the transcatheter approach forward into a clinically feasible alternative to surgery for selected patients with severe MR.

Original languageEnglish
JournalJournal of Cardiovascular Surgery
Volume57
Issue number3
Pages (from-to)381-92
Number of pages12
ISSN0021-9509
Publication statusPublished - Jun 2016

    Research areas

  • Anatomic Landmarks, Cardiac Catheterization, Heart Valve Prosthesis Implantation, Humans, Mitral Valve, Mitral Valve Insufficiency, Risk Assessment, Risk Factors, Journal Article

ID: 49805247