Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Anaphylaxis to ethylene oxide - a rare and overlooked phenomenon?

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Impact of Physician-staffed Helicopters on Pre-hospital Patient Outcomes: a systematic review

    Research output: Contribution to journalReviewResearchpeer-review

  2. Hypothermic to ischemic ratio and mortality in post-cardiac arrest patients

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Response letter to comments made by J. G. Förster, M. Pitkänen

    Research output: Contribution to journalLetterResearchpeer-review

  1. Perioperative anaphylaxis in children: Etiology, time sequence, and patterns of clinical reactivity

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. An EAACI position paper on the investigation of perioperative immediate hypersensitivity reactions

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Delayed cerebral ischaemia in patients with aneurysmal subarachnoid haemorrhage: Functional outcome and long-term mortality

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Soluble ST2 links inflammation to outcome after subarachnoid hemorrhage

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Undersøgelse og diagnostik af allergiske lidelser en kort gennemgang for tandlæger

    Research output: Contribution to journalJournal articleCommunication

View graph of relations
Spina bifida patients have been reported to be at increased risk of anaphylactic reactions during general anaesthesia. Following a reaction, latex is often incriminated as spina bifida patients are known to have an increased incidence of latex allergy. Ethylene oxide (EO) has recently been suggested to be an alternative cause, but in many cases reported in the literature, it seems that EO has not been considered as a cause. EO is a highly reactive gas widely used to sterilise heat-sensitive medical devices, and traces of EO can be found in many of the same products as latex. We present the case of a spina bifida patient with a known latex allergy, where EO was found to be the cause of an anaphylactic reaction during general anaesthesia. In addition, we describe measures taken during preparation of a subsequent general anaesthesia to minimise exposure to EO. Spina bifida patients seem to be at increased risk of sensitisation against EO due to repeated exposure, but only limited literature is available. To ensure that EO is considered as a cause in these cases, we recommend that testing for latex and EO go hand in hand following an anaphylactic reaction in this high-risk population.
Original languageEnglish
JournalActa Anaesthesiologica Scandinavica
Volume55
Issue number10
Pages (from-to)1279-82
Number of pages4
ISSN0001-5172
DOIs
Publication statusPublished - 2011

ID: 34673685