Analysis of the treatment effect on recurrent bleeding and death in patients with cirrhosis and esophageal varices: multistage competing-risks model compared to conventional methods. The Copenhagen Esophageal Varices Sclerotherapy Project

B L Thomsen; T I Sørensen

doi:10.1016/S0168-8278(98)80209-2

Analysis of the treatment effect on recurrent bleeding and death in patients with cirrhosis and esophageal varices: multistage competing-risks model compared to conventional methods. The Copenhagen Esophageal Varices Sclerotherapy Project

B L Thomsen, T I Sørensen

Copenhagen Trial Unit

12 Citations (Scopus)

Abstract

Multiple recurrences of bleeding with high mortality in cirrhosis with esophageal varices have been inadequately analyzed in previous trials. We propose analysis by the multistage competing-risks model, specifying the effect on overall mortality as an effect on mortality during bleeding, rate of cessation of bleeding, mortality rate without bleeding, and rate of rebleeding.

Original language	English
Journal	Journal of Hepatology
Volume	28
Issue number	1
Pages (from-to)	107-14
Number of pages	8
ISSN	0168-8278
DOIs	https://doi.org/10.1016/S0168-8278(98)80209-2
Publication status	Published - Jan 1998

Keywords

Denmark
Esophageal and Gastric Varices
Follow-Up Studies
Gastrointestinal Hemorrhage
Humans
Liver Cirrhosis
Models, Statistical
Recurrence
Regression Analysis
Risk Factors
Sclerotherapy
Time Factors

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Analysis of the treatment effect on recurrent bleeding and death in patients with cirrhosis and esophageal varices: multistage competing-risks model compared to conventional methods. The Copenhagen Esophageal Varices Sclerotherapy Project. / Thomsen, B L; Sørensen, T I.
In: Journal of Hepatology, Vol. 28, No. 1, 01.1998, p. 107-14.

Research output: Contribution to journal › Journal article › Research › peer-review

Thomsen, BL & Sørensen, TI 1998, 'Analysis of the treatment effect on recurrent bleeding and death in patients with cirrhosis and esophageal varices: multistage competing-risks model compared to conventional methods. The Copenhagen Esophageal Varices Sclerotherapy Project', Journal of Hepatology, vol. 28, no. 1, pp. 107-14. https://doi.org/10.1016/S0168-8278(98)80209-2

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abstract = "Multiple recurrences of bleeding with high mortality in cirrhosis with esophageal varices have been inadequately analyzed in previous trials. We propose analysis by the multistage competing-risks model, specifying the effect on overall mortality as an effect on mortality during bleeding, rate of cessation of bleeding, mortality rate without bleeding, and rate of rebleeding.",

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KW - Denmark

KW - Esophageal and Gastric Varices

KW - Follow-Up Studies

KW - Gastrointestinal Hemorrhage

KW - Humans

KW - Liver Cirrhosis

KW - Models, Statistical

KW - Recurrence

KW - Regression Analysis

KW - Risk Factors

KW - Sclerotherapy

KW - Time Factors

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Analysis of the treatment effect on recurrent bleeding and death in patients with cirrhosis and esophageal varices: multistage competing-risks model compared to conventional methods. The Copenhagen Esophageal Varices Sclerotherapy Project

Abstract

Keywords

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