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An update on the clinical approach to giant cell arteritis

Rachel Piccus, Michael Stormly Hansen, Steffen Hamann, Susan P Mollan*

*Corresponding author for this work
7 Citations (Scopus)

Abstract

Recent national and international guidance from rheumatology societies have reflected the advances in evidence for both the investigation and management of giant cell arteritis. Cranial ultrasound reduces diagnostic delay and improves clinical outcomes. Immediate high-dose glucocorticoids remain the standard treatment for giant cell arteritis. Randomised controlled trial evidence using tocilizumab, an interleukin-6 receptor antagonist, has been shown to have good clinical efficacy with glucocorticoid sparing effects. Overall patient outcomes appear to be improved by formalising pathways for diagnosis to include clinical experts' opinion early in decision making.

Original languageEnglish
JournalClinical Medicine
Volume22
Issue number2
Pages (from-to)107-111
Number of pages5
ISSN1470-2118
DOIs
Publication statusPublished - 2022

Keywords

  • giant cell arteritis
  • temporal arteritis
  • temporal artery biopsy
  • tocilizumab
  • ultrasound

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