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An update on head and neck cancer: new entities and their histopathology, molecular background, treatment, and outcome

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@article{8e88637ec93d4b089273a7bcaa8cd202,
title = "An update on head and neck cancer: new entities and their histopathology, molecular background, treatment, and outcome",
abstract = "The head and neck region harbor numerous specialized tissues of all lineages giving rise to a plethora of different malignancies. In recent years, new types and subtypes of cancer has been described here due to the recognition of their histological and molecular characteristics. Some have been formally accepted in the most recent classifications from the World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) as distinct diseases due to characteristics in clinical presentation, outcome, and treatment. In particular, this applies to malignancies of the salivary gland, sinonasal tract, and oropharynx. In this overview, we present the most recent developments in the classification, histopathological characteristics, and molecular features of head and neck cancer. The clinical and radiological characteristics, outcome, and treatment options including perspectives for targeted therapies, are discussed.",
keywords = "Electrochemotherapy, Head and Neck Neoplasms/classification, Humans, Melanoma/pathology, Molecular Targeted Therapy, Mouth Neoplasms/pathology, Nose Neoplasms/pathology, Oropharyngeal Neoplasms/pathology, Prognosis, Salivary Gland Neoplasms/pathology",
author = "Simon Andreasen and Katalin Kiss and Mikkelsen, {Lauge Hjorth} and Channir, {Hani Ibrahim} and Plaschke, {Christina Caroline} and Melchior, {Linea Cecilie} and Eriksen, {Jesper Grau} and Irene Wessel",
note = "{\circledC} 2018 APMIS. Published by John Wiley & Sons Ltd.",
year = "2019",
month = "5",
doi = "10.1111/apm.12901",
language = "English",
volume = "127",
pages = "240--264",
journal = "APMIS - Journal of Pathology, Microbiology and Immunology",
issn = "0903-4641",
publisher = "Wiley Online",
number = "5",

}

RIS

TY - JOUR

T1 - An update on head and neck cancer

T2 - new entities and their histopathology, molecular background, treatment, and outcome

AU - Andreasen, Simon

AU - Kiss, Katalin

AU - Mikkelsen, Lauge Hjorth

AU - Channir, Hani Ibrahim

AU - Plaschke, Christina Caroline

AU - Melchior, Linea Cecilie

AU - Eriksen, Jesper Grau

AU - Wessel, Irene

N1 - © 2018 APMIS. Published by John Wiley & Sons Ltd.

PY - 2019/5

Y1 - 2019/5

N2 - The head and neck region harbor numerous specialized tissues of all lineages giving rise to a plethora of different malignancies. In recent years, new types and subtypes of cancer has been described here due to the recognition of their histological and molecular characteristics. Some have been formally accepted in the most recent classifications from the World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) as distinct diseases due to characteristics in clinical presentation, outcome, and treatment. In particular, this applies to malignancies of the salivary gland, sinonasal tract, and oropharynx. In this overview, we present the most recent developments in the classification, histopathological characteristics, and molecular features of head and neck cancer. The clinical and radiological characteristics, outcome, and treatment options including perspectives for targeted therapies, are discussed.

AB - The head and neck region harbor numerous specialized tissues of all lineages giving rise to a plethora of different malignancies. In recent years, new types and subtypes of cancer has been described here due to the recognition of their histological and molecular characteristics. Some have been formally accepted in the most recent classifications from the World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) as distinct diseases due to characteristics in clinical presentation, outcome, and treatment. In particular, this applies to malignancies of the salivary gland, sinonasal tract, and oropharynx. In this overview, we present the most recent developments in the classification, histopathological characteristics, and molecular features of head and neck cancer. The clinical and radiological characteristics, outcome, and treatment options including perspectives for targeted therapies, are discussed.

KW - Electrochemotherapy

KW - Head and Neck Neoplasms/classification

KW - Humans

KW - Melanoma/pathology

KW - Molecular Targeted Therapy

KW - Mouth Neoplasms/pathology

KW - Nose Neoplasms/pathology

KW - Oropharyngeal Neoplasms/pathology

KW - Prognosis

KW - Salivary Gland Neoplasms/pathology

U2 - 10.1111/apm.12901

DO - 10.1111/apm.12901

M3 - Review

VL - 127

SP - 240

EP - 264

JO - APMIS - Journal of Pathology, Microbiology and Immunology

JF - APMIS - Journal of Pathology, Microbiology and Immunology

SN - 0903-4641

IS - 5

ER -

ID: 58278143