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The Capital Region of Denmark - a part of Copenhagen University Hospital
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An update on head and neck cancer: new entities and their histopathology, molecular background, treatment, and outcome

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  1. A case of false-positive pneumococcal urinary antigen test in a bacteremic Streptococcus agalactiae infection

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  2. Incidence and malignant transformation of glottic precursor lesions in Denmark

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The head and neck region harbor numerous specialized tissues of all lineages giving rise to a plethora of different malignancies. In recent years, new types and subtypes of cancer has been described here due to the recognition of their histological and molecular characteristics. Some have been formally accepted in the most recent classifications from the World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) as distinct diseases due to characteristics in clinical presentation, outcome, and treatment. In particular, this applies to malignancies of the salivary gland, sinonasal tract, and oropharynx. In this overview, we present the most recent developments in the classification, histopathological characteristics, and molecular features of head and neck cancer. The clinical and radiological characteristics, outcome, and treatment options including perspectives for targeted therapies, are discussed.

Original languageEnglish
JournalAPMIS - Journal of Pathology, Microbiology and Immunology
Volume127
Issue number5
Pages (from-to)240-264
Number of pages25
ISSN0903-4641
DOIs
Publication statusPublished - May 2019

    Research areas

  • Electrochemotherapy, Head and Neck Neoplasms/classification, Humans, Melanoma/pathology, Molecular Targeted Therapy, Mouth Neoplasms/pathology, Nose Neoplasms/pathology, Oropharyngeal Neoplasms/pathology, Prognosis, Salivary Gland Neoplasms/pathology

ID: 58278143