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An acoustic myography functional assessment of cerebral palsy subjects compared to healthy controls during physical exercise

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@article{6fa6a2f3b4374cea9b4facb5983f8928,
title = "An acoustic myography functional assessment of cerebral palsy subjects compared to healthy controls during physical exercise",
abstract = "Individuals with cerebral palsy (CP) participate in reduced levels of physical activity and spend an increased amount of time in a sedentary state compared with healthy control subjects. Whether this in part can be explained by impaired muscle function is still unclear. The aim of the present study was to elucidate differences in muscle fibre recruitment during treadmill exercise between CP subjects and healthy age-, sex- and BMI-matched controls. This is a case-control study. Acoustic myography (AMG), a method recording fibre use and efficiency from contracting muscles, was applied during a period of treadmill exercise. The recorded AMG parameters revealed that the CP subjects had a significantly lower initial S-score (spatial summation) than the controls (P < 0.01). However, the T-score (temporal summation) and the E-score (efficiency) showed no significant differences between individuals with CP and the healthy control subjects. The present findings indicate that CP subjects use a higher degree of spatial summation (more fibres recruited) to keep up the same speed during treadmill exercise when compared to healthy matched control subjects. Our results suggest that individuals with CP have a tendency to recruit far more muscle fibres during bouts of exercise than healthy individuals. This may partly explain why CP subjects experience premature fatigue.",
author = "Jessica Pingel and Andersen, {Ida Torp} and Rikke Broholm and Anja Harder and Bartels, {Else Marie} and Jens B{\"u}low and Adrian Harrison",
year = "2019",
month = "3",
doi = "10.1007/s10974-019-09516-y",
language = "English",
volume = "40",
pages = "53--58",
journal = "Journal of muscle research and cell motility",
issn = "0142-4319",
number = "1",

}

RIS

TY - JOUR

T1 - An acoustic myography functional assessment of cerebral palsy subjects compared to healthy controls during physical exercise

AU - Pingel, Jessica

AU - Andersen, Ida Torp

AU - Broholm, Rikke

AU - Harder, Anja

AU - Bartels, Else Marie

AU - Bülow, Jens

AU - Harrison, Adrian

PY - 2019/3

Y1 - 2019/3

N2 - Individuals with cerebral palsy (CP) participate in reduced levels of physical activity and spend an increased amount of time in a sedentary state compared with healthy control subjects. Whether this in part can be explained by impaired muscle function is still unclear. The aim of the present study was to elucidate differences in muscle fibre recruitment during treadmill exercise between CP subjects and healthy age-, sex- and BMI-matched controls. This is a case-control study. Acoustic myography (AMG), a method recording fibre use and efficiency from contracting muscles, was applied during a period of treadmill exercise. The recorded AMG parameters revealed that the CP subjects had a significantly lower initial S-score (spatial summation) than the controls (P < 0.01). However, the T-score (temporal summation) and the E-score (efficiency) showed no significant differences between individuals with CP and the healthy control subjects. The present findings indicate that CP subjects use a higher degree of spatial summation (more fibres recruited) to keep up the same speed during treadmill exercise when compared to healthy matched control subjects. Our results suggest that individuals with CP have a tendency to recruit far more muscle fibres during bouts of exercise than healthy individuals. This may partly explain why CP subjects experience premature fatigue.

AB - Individuals with cerebral palsy (CP) participate in reduced levels of physical activity and spend an increased amount of time in a sedentary state compared with healthy control subjects. Whether this in part can be explained by impaired muscle function is still unclear. The aim of the present study was to elucidate differences in muscle fibre recruitment during treadmill exercise between CP subjects and healthy age-, sex- and BMI-matched controls. This is a case-control study. Acoustic myography (AMG), a method recording fibre use and efficiency from contracting muscles, was applied during a period of treadmill exercise. The recorded AMG parameters revealed that the CP subjects had a significantly lower initial S-score (spatial summation) than the controls (P < 0.01). However, the T-score (temporal summation) and the E-score (efficiency) showed no significant differences between individuals with CP and the healthy control subjects. The present findings indicate that CP subjects use a higher degree of spatial summation (more fibres recruited) to keep up the same speed during treadmill exercise when compared to healthy matched control subjects. Our results suggest that individuals with CP have a tendency to recruit far more muscle fibres during bouts of exercise than healthy individuals. This may partly explain why CP subjects experience premature fatigue.

U2 - 10.1007/s10974-019-09516-y

DO - 10.1007/s10974-019-09516-y

M3 - Journal article

VL - 40

SP - 53

EP - 58

JO - Journal of muscle research and cell motility

JF - Journal of muscle research and cell motility

SN - 0142-4319

IS - 1

ER -

ID: 57799987