An acoustic myography functional assessment of cerebral palsy subjects compared to healthy controls during physical exercise

Jessica Pingel, Ida Torp Andersen, Rikke Broholm, Anja Harder, Else Marie Bartels, Jens Bülow, Adrian Harrison

8 Citations (Scopus)

Abstract

Individuals with cerebral palsy (CP) participate in reduced levels of physical activity and spend an increased amount of time in a sedentary state compared with healthy control subjects. Whether this in part can be explained by impaired muscle function is still unclear. The aim of the present study was to elucidate differences in muscle fibre recruitment during treadmill exercise between CP subjects and healthy age-, sex- and BMI-matched controls. This is a case-control study. Acoustic myography (AMG), a method recording fibre use and efficiency from contracting muscles, was applied during a period of treadmill exercise. The recorded AMG parameters revealed that the CP subjects had a significantly lower initial S-score (spatial summation) than the controls (P < 0.01). However, the T-score (temporal summation) and the E-score (efficiency) showed no significant differences between individuals with CP and the healthy control subjects. The present findings indicate that CP subjects use a higher degree of spatial summation (more fibres recruited) to keep up the same speed during treadmill exercise when compared to healthy matched control subjects. Our results suggest that individuals with CP have a tendency to recruit far more muscle fibres during bouts of exercise than healthy individuals. This may partly explain why CP subjects experience premature fatigue.

Original languageEnglish
JournalJournal of muscle research and cell motility
Volume40
Issue number1
Pages (from-to)53-58
Number of pages6
ISSN0142-4319
DOIs
Publication statusPublished - Mar 2019

Keywords

  • Acoustic myography
  • Cerebral palsy
  • Muscle fatigue
  • Muscle fibre activity

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