Allopurinol increases DNA-thioguanine nucleotides during maintenance therapy in pediatric acute lymphoblastic leukemia

Jonatan Källström; Riitta Niinimäki; Johan Fredlund; Hartmut Vogt; Laura S Korhonen; Anders Castor; Kjeld Schmiegelow; Maria Thastrup; Torben Ek

doi:10.3324/haematol.2025.288872

Allopurinol increases DNA-thioguanine nucleotides during maintenance therapy in pediatric acute lymphoblastic leukemia

Jonatan Källström, Riitta Niinimäki, Johan Fredlund, Hartmut Vogt, Laura S Korhonen, Anders Castor, Kjeld Schmiegelow, Maria Thastrup, Torben Ek

Department of Paediatrics and Adolescent Medicine

Abstract

Not available.

Original language	English
Journal	Haematologica
ISSN	0390-6078
DOIs	https://doi.org/10.3324/haematol.2025.288872
Publication status	E-pub ahead of print - 4 Dec 2025

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10.3324/haematol.2025.288872Licence: CC BY-NC

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@article{4b760177b7d042fc8b803c0317749835,

title = "Allopurinol increases DNA-thioguanine nucleotides during maintenance therapy in pediatric acute lymphoblastic leukemia",

abstract = "Not available.",

author = "Jonatan K{\"a}llstr{\"o}m and Riitta Niinim{\"a}ki and Johan Fredlund and Hartmut Vogt and Korhonen, \{Laura S\} and Anders Castor and Kjeld Schmiegelow and Maria Thastrup and Torben Ek",

year = "2025",

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doi = "10.3324/haematol.2025.288872",

language = "English",

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TY - JOUR

T1 - Allopurinol increases DNA-thioguanine nucleotides during maintenance therapy in pediatric acute lymphoblastic leukemia

AU - Källström, Jonatan

AU - Niinimäki, Riitta

AU - Fredlund, Johan

AU - Vogt, Hartmut

AU - Korhonen, Laura S

AU - Castor, Anders

AU - Schmiegelow, Kjeld

AU - Thastrup, Maria

AU - Ek, Torben

PY - 2025/12/4

Y1 - 2025/12/4

N2 - Not available.

AB - Not available.

U2 - 10.3324/haematol.2025.288872

DO - 10.3324/haematol.2025.288872

M3 - Comment/debate

C2 - 41342181

SN - 0390-6078

JO - Haematologica

JF - Haematologica

ER -

Allopurinol increases DNA-thioguanine nucleotides during maintenance therapy in pediatric acute lymphoblastic leukemia

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