Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis

N Pedersen; S Larsen; J B Seidelin; O H Nielsen

Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis

N Pedersen, S Larsen, J B Seidelin, O H Nielsen

18 Citations (Scopus)

Abstract

Cytokines are markers of acute pancreatic inflammation and essential for distant organ injury, but they also stimulate pancreatic fibrogenesis and are thus involved in the progression from acute pancreatitis to chronic pancreatic injury and fibrosis. The aim of this study was to evaluate the circulating levels of IL-6, MCP-1, TGF-beta1, IGF-1 and IGFBP-3 in patients with alcoholic chronic pancreatitis (CP).

Original language	English
Journal	Scandinavian Journal of Gastroenterology
Volume	39
Issue number	3
Pages (from-to)	277-82
Number of pages	6
ISSN	0036-5521
Publication status	Published - 2004

Keywords

Adult
Aged
Case-Control Studies
Central Nervous System Depressants
Chemokine CCL2
Ethanol
Humans
Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor I
Interleukin-6
Male
Middle Aged
Pancreatitis, Alcoholic
Transforming Growth Factor beta
Transforming Growth Factor beta1

Cite this

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title = "Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis",

abstract = "Cytokines are markers of acute pancreatic inflammation and essential for distant organ injury, but they also stimulate pancreatic fibrogenesis and are thus involved in the progression from acute pancreatitis to chronic pancreatic injury and fibrosis. The aim of this study was to evaluate the circulating levels of IL-6, MCP-1, TGF-beta1, IGF-1 and IGFBP-3 in patients with alcoholic chronic pancreatitis (CP).",

keywords = "Adult, Aged, Case-Control Studies, Central Nervous System Depressants, Chemokine CCL2, Ethanol, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, Interleukin-6, Male, Middle Aged, Pancreatitis, Alcoholic, Transforming Growth Factor beta, Transforming Growth Factor beta1",

author = "N Pedersen and S Larsen and Seidelin, \{J B\} and Nielsen, \{O H\}",

year = "2004",

language = "English",

volume = "39",

pages = "277--82",

journal = "Scandinavian Journal of Gastroenterology",

issn = "0036-5521",

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TY - JOUR

T1 - Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis

AU - Pedersen, N

AU - Larsen, S

AU - Seidelin, J B

AU - Nielsen, O H

PY - 2004

Y1 - 2004

N2 - Cytokines are markers of acute pancreatic inflammation and essential for distant organ injury, but they also stimulate pancreatic fibrogenesis and are thus involved in the progression from acute pancreatitis to chronic pancreatic injury and fibrosis. The aim of this study was to evaluate the circulating levels of IL-6, MCP-1, TGF-beta1, IGF-1 and IGFBP-3 in patients with alcoholic chronic pancreatitis (CP).

AB - Cytokines are markers of acute pancreatic inflammation and essential for distant organ injury, but they also stimulate pancreatic fibrogenesis and are thus involved in the progression from acute pancreatitis to chronic pancreatic injury and fibrosis. The aim of this study was to evaluate the circulating levels of IL-6, MCP-1, TGF-beta1, IGF-1 and IGFBP-3 in patients with alcoholic chronic pancreatitis (CP).

KW - Adult

KW - Aged

KW - Case-Control Studies

KW - Central Nervous System Depressants

KW - Chemokine CCL2

KW - Ethanol

KW - Humans

KW - Insulin-Like Growth Factor Binding Protein 3

KW - Insulin-Like Growth Factor I

KW - Interleukin-6

KW - Male

KW - Middle Aged

KW - Pancreatitis, Alcoholic

KW - Transforming Growth Factor beta

KW - Transforming Growth Factor beta1

UR - https://www.scopus.com/pages/publications/1642393861

M3 - Journal article

C2 - 15074399

SN - 0036-5521

VL - 39

SP - 277

EP - 282

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

IS - 3

ER -

Alcohol modulates circulating levels of interleukin-6 and monocyte chemoattractant protein-1 in chronic pancreatitis

Abstract

Keywords

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