Akut, svær leverinsufficiens forårsaget af binyretumor hos nyfødt

Jane Maestri Ditlevsen; Nina Kvist; Lars Søndergaard Johansen; Marianne Hørby Jørgensen; Birthe Merete Henriksen; Catherine Rechnitzer; Ane Lando; Bodil Laub Petersen; Liselotte Højgaard; Lise Borgwardt

Akut, svær leverinsufficiens forårsaget af binyretumor hos nyfødt

Translated title of the contribution: Acute, severe liver insufficiency caused by extrahepatic biliary atresia in a newborn

Jane Maestri Ditlevsen, Nina Kvist, Lars Søndergaard Johansen, Marianne Hørby Jørgensen, Birthe Merete Henriksen, Catherine Rechnitzer, Ane Lando, Bodil Laub Petersen, Liselotte Højgaard, Lise Borgwardt

Abstract

A newborn female was hospitalized due to metabolic acidosis and conjugated hyperbilirubinaemia. Extrahepatic biliary atresia (EHBA) was suspected why a (99m)Tc-mebrofenin cholescintigraphy was performed. It showed poor hepatocyte tracer uptake and no drainage to the gut. The hepatocyte dysfunction was caused by an obstructing adrenal gland neuroblastoma later visualised by ultrasound and MRI. The cholescintigraphy is a non-invasive modality to exclude or confirm the suspicion of EHBA. Furthermore neonatal conjugated hyperbilirubinaemia demands the use of a multimodality imaging strategy for differential diagnosis to EHBA.

Translated title of the contribution	Acute, severe liver insufficiency caused by extrahepatic biliary atresia in a newborn
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	175
Issue number	17
Pages (from-to)	1195-6
Number of pages	2
ISSN	0041-5782
Publication status	Published - 22 Apr 2013

Cite this

@article{c78a739f967248529a2af7c2600f9d8b,

title = "Akut, sv{\ae}r leverinsufficiens for{\aa}rsaget af binyretumor hos nyf{\o}dt",

abstract = "A newborn female was hospitalized due to metabolic acidosis and conjugated hyperbilirubinaemia. Extrahepatic biliary atresia (EHBA) was suspected why a (99m)Tc-mebrofenin cholescintigraphy was performed. It showed poor hepatocyte tracer uptake and no drainage to the gut. The hepatocyte dysfunction was caused by an obstructing adrenal gland neuroblastoma later visualised by ultrasound and MRI. The cholescintigraphy is a non-invasive modality to exclude or confirm the suspicion of EHBA. Furthermore neonatal conjugated hyperbilirubinaemia demands the use of a multimodality imaging strategy for differential diagnosis to EHBA.",

keywords = "Acute Disease, Adrenal Gland Neoplasms, Biliary Atresia, Female, Hepatic Insufficiency, Humans, Hyperbilirubinemia, Neonatal, Infant, Newborn, Neuroblastoma, Radiopharmaceuticals, Technetium Tc 99m Diethyl-iminodiacetic Acid, Treatment Outcome",

author = "{Maestri Ditlevsen}, Jane and Nina Kvist and Johansen, {Lars S{\o}ndergaard} and J{\o}rgensen, {Marianne H{\o}rby} and Henriksen, {Birthe Merete} and Catherine Rechnitzer and Ane Lando and Petersen, {Bodil Laub} and Liselotte H{\o}jgaard and Lise Borgwardt",

year = "2013",

month = apr,

day = "22",

language = "Dansk",

volume = "175",

pages = "1195--6",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "17",

}

TY - JOUR

T1 - Akut, svær leverinsufficiens forårsaget af binyretumor hos nyfødt

AU - Maestri Ditlevsen, Jane

AU - Kvist, Nina

AU - Johansen, Lars Søndergaard

AU - Jørgensen, Marianne Hørby

AU - Henriksen, Birthe Merete

AU - Rechnitzer, Catherine

AU - Lando, Ane

AU - Petersen, Bodil Laub

AU - Højgaard, Liselotte

AU - Borgwardt, Lise

PY - 2013/4/22

Y1 - 2013/4/22

N2 - A newborn female was hospitalized due to metabolic acidosis and conjugated hyperbilirubinaemia. Extrahepatic biliary atresia (EHBA) was suspected why a (99m)Tc-mebrofenin cholescintigraphy was performed. It showed poor hepatocyte tracer uptake and no drainage to the gut. The hepatocyte dysfunction was caused by an obstructing adrenal gland neuroblastoma later visualised by ultrasound and MRI. The cholescintigraphy is a non-invasive modality to exclude or confirm the suspicion of EHBA. Furthermore neonatal conjugated hyperbilirubinaemia demands the use of a multimodality imaging strategy for differential diagnosis to EHBA.

AB - A newborn female was hospitalized due to metabolic acidosis and conjugated hyperbilirubinaemia. Extrahepatic biliary atresia (EHBA) was suspected why a (99m)Tc-mebrofenin cholescintigraphy was performed. It showed poor hepatocyte tracer uptake and no drainage to the gut. The hepatocyte dysfunction was caused by an obstructing adrenal gland neuroblastoma later visualised by ultrasound and MRI. The cholescintigraphy is a non-invasive modality to exclude or confirm the suspicion of EHBA. Furthermore neonatal conjugated hyperbilirubinaemia demands the use of a multimodality imaging strategy for differential diagnosis to EHBA.

KW - Acute Disease

KW - Adrenal Gland Neoplasms

KW - Biliary Atresia

KW - Female

KW - Hepatic Insufficiency

KW - Humans

KW - Hyperbilirubinemia, Neonatal

KW - Infant, Newborn

KW - Neuroblastoma

KW - Radiopharmaceuticals

KW - Technetium Tc 99m Diethyl-iminodiacetic Acid

KW - Treatment Outcome

M3 - Tidsskriftartikel

C2 - 23651786

SN - 0041-5782

VL - 175

SP - 1195

EP - 1196

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 17

ER -

Akut, svær leverinsufficiens forårsaget af binyretumor hos nyfødt

Abstract

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