Age-Related Prevalence of Open Ductus Arteriosus in Full-Term Newborns

Anton Friis Mariager; Alberte Hammeken; Mikkel Malham; Anna Axelsson Raja; Anna Sellmer; Signe Levring Skjellerup; Raheel Altaf Raja; Johan Navne; Anne-Sophie Sillesen; Niels Vejlstrup; Henning Bundgaard; Kasper Karmark Iversen; Ester Garne; Dorthe Lisbeth Jeppesen

doi:10.1159/000529842

Age-Related Prevalence of Open Ductus Arteriosus in Full-Term Newborns

Anton Friis Mariager^*, Alberte Hammeken, Mikkel Malham, Anna Axelsson Raja, Anna Sellmer, Signe Levring Skjellerup, Raheel Altaf Raja, Johan Navne, Anne-Sophie Sillesen, Niels Vejlstrup, Henning Bundgaard, Kasper Karmark Iversen, Ester Garne, Dorthe Lisbeth Jeppesen

^*Corresponding author for this work

Abstract

BACKGROUND: The ductus arteriosus is part of the fetal circulation. Normally, the vessel closes during the cardiac transition. Delayed closure is associated with complications. The aim of this study was to evaluate the age-related prevalence of open ductus arteriosus in full-term neonates.

METHODS: Echocardiograms were collected in the population study, the Copenhagen Baby Heart Study. The present study included full-term neonates with an echocardiogram performed within 28 days after birth. All echocardiograms were reviewed to assess ductus arteriosus patency.

RESULTS: A total of 21,649 neonates were included. In neonates examined at day zero and day seven, an open ductus arteriosus was found in 36% and 0.6%, respectively. Beyond day seven, the prevalence remained stable at 0.6%.

CONCLUSION: More than one-third of full-term neonates had an open ductus arteriosus on the first day of life, declining rapidly within the first week and stabilizing below 1% after day seven.

Original language	English
Journal	Neonatology
Volume	120
Issue number	4
Pages (from-to)	527-531
Number of pages	5
ISSN	1661-7800
DOIs	https://doi.org/10.1159/000529842
Publication status	Published - 2023

Keywords

Ductus Arteriosus, Patent/diagnostic imaging
Ductus Arteriosus/diagnostic imaging
Echocardiography
Female
Humans
Infant, Newborn
Parturition
Pregnancy
Prevalence
Patent ductus arteriosus
Neonatology
Ductus arteriosus
Congenital heart defect

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title = "Age-Related Prevalence of Open Ductus Arteriosus in Full-Term Newborns",

abstract = "BACKGROUND: The ductus arteriosus is part of the fetal circulation. Normally, the vessel closes during the cardiac transition. Delayed closure is associated with complications. The aim of this study was to evaluate the age-related prevalence of open ductus arteriosus in full-term neonates.METHODS: Echocardiograms were collected in the population study, the Copenhagen Baby Heart Study. The present study included full-term neonates with an echocardiogram performed within 28 days after birth. All echocardiograms were reviewed to assess ductus arteriosus patency.RESULTS: A total of 21,649 neonates were included. In neonates examined at day zero and day seven, an open ductus arteriosus was found in 36% and 0.6%, respectively. Beyond day seven, the prevalence remained stable at 0.6%.CONCLUSION: More than one-third of full-term neonates had an open ductus arteriosus on the first day of life, declining rapidly within the first week and stabilizing below 1% after day seven.",

keywords = "Ductus Arteriosus, Patent/diagnostic imaging, Ductus Arteriosus/diagnostic imaging, Echocardiography, Female, Humans, Infant, Newborn, Parturition, Pregnancy, Prevalence, Patent ductus arteriosus, Neonatology, Ductus arteriosus, Congenital heart defect",

author = "Mariager, {Anton Friis} and Alberte Hammeken and Mikkel Malham and Raja, {Anna Axelsson} and Anna Sellmer and Skjellerup, {Signe Levring} and Raja, {Raheel Altaf} and Johan Navne and Anne-Sophie Sillesen and Niels Vejlstrup and Henning Bundgaard and Iversen, {Kasper Karmark} and Ester Garne and Jeppesen, {Dorthe Lisbeth}",

note = "{\textcopyright} 2023 The Author(s). Published by S. Karger AG, Basel.",

year = "2023",

doi = "10.1159/000529842",

language = "English",

volume = "120",

pages = "527--531",

journal = "Neonatology",

issn = "1661-7800",

publisher = "S./Karger AG",

number = "4",

}

TY - JOUR

T1 - Age-Related Prevalence of Open Ductus Arteriosus in Full-Term Newborns

AU - Mariager, Anton Friis

AU - Hammeken, Alberte

AU - Malham, Mikkel

AU - Raja, Anna Axelsson

AU - Sellmer, Anna

AU - Skjellerup, Signe Levring

AU - Raja, Raheel Altaf

AU - Navne, Johan

AU - Sillesen, Anne-Sophie

AU - Vejlstrup, Niels

AU - Bundgaard, Henning

AU - Iversen, Kasper Karmark

AU - Garne, Ester

AU - Jeppesen, Dorthe Lisbeth

PY - 2023

Y1 - 2023

N2 - BACKGROUND: The ductus arteriosus is part of the fetal circulation. Normally, the vessel closes during the cardiac transition. Delayed closure is associated with complications. The aim of this study was to evaluate the age-related prevalence of open ductus arteriosus in full-term neonates.METHODS: Echocardiograms were collected in the population study, the Copenhagen Baby Heart Study. The present study included full-term neonates with an echocardiogram performed within 28 days after birth. All echocardiograms were reviewed to assess ductus arteriosus patency.RESULTS: A total of 21,649 neonates were included. In neonates examined at day zero and day seven, an open ductus arteriosus was found in 36% and 0.6%, respectively. Beyond day seven, the prevalence remained stable at 0.6%.CONCLUSION: More than one-third of full-term neonates had an open ductus arteriosus on the first day of life, declining rapidly within the first week and stabilizing below 1% after day seven.

AB - BACKGROUND: The ductus arteriosus is part of the fetal circulation. Normally, the vessel closes during the cardiac transition. Delayed closure is associated with complications. The aim of this study was to evaluate the age-related prevalence of open ductus arteriosus in full-term neonates.METHODS: Echocardiograms were collected in the population study, the Copenhagen Baby Heart Study. The present study included full-term neonates with an echocardiogram performed within 28 days after birth. All echocardiograms were reviewed to assess ductus arteriosus patency.RESULTS: A total of 21,649 neonates were included. In neonates examined at day zero and day seven, an open ductus arteriosus was found in 36% and 0.6%, respectively. Beyond day seven, the prevalence remained stable at 0.6%.CONCLUSION: More than one-third of full-term neonates had an open ductus arteriosus on the first day of life, declining rapidly within the first week and stabilizing below 1% after day seven.

KW - Ductus Arteriosus, Patent/diagnostic imaging

KW - Ductus Arteriosus/diagnostic imaging

KW - Echocardiography

KW - Female

KW - Humans

KW - Infant, Newborn

KW - Parturition

KW - Pregnancy

KW - Prevalence

KW - Patent ductus arteriosus

KW - Neonatology

KW - Ductus arteriosus

KW - Congenital heart defect

UR - https://pubmed.ncbi.nlm.nih.gov/37285834/

U2 - 10.1159/000529842

DO - 10.1159/000529842

M3 - Journal article

C2 - 37285834

SN - 1661-7800

VL - 120

SP - 527

EP - 531

JO - Neonatology

JF - Neonatology

IS - 4

ER -

Age-Related Prevalence of Open Ductus Arteriosus in Full-Term Newborns

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