Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Aerobic anti-gravity exercise in patients with Charcot-Marie-Tooth disease types 1A and X: A pilot study

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Neuroimaging markers of global cognition in early Alzheimer's disease: A magnetic resonance imaging-electroencephalography study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Brain serotonin 4 receptor binding is inversely associated with verbal memory recall

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Genetic variation and cognitive dysfunction in opioid-treated patients with cancer

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Morbidity in early Parkinson's disease and prior to diagnosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Linking variability in brain chemistry and circuit function through multimodal human neuroimaging

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Hydroxylated Long-Chain Acylcarnitines are Biomarkers of Mitochondrial Myopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Fat oxidation is impaired during exercise in lipin-1 deficiency

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Background: Charcot-Marie-Tooth (CMT) disease is a hereditary neuropathy associated with impaired walking capacity. Some patients are too weak in the lower extremity muscles to walk at gravity with sufficient intensity or duration to gain benefit.

Aim: The aim was to investigate the effect of aerobic anti-gravity exercise in weak patients with CMT 1A and X.

Methods: Five adult patients performed moderate-intensity aerobic anti-gravity exercise 3/week for 10 weeks.

Results: There was a significant positive difference in Berg balance scale and postural stability test between test occasions, and walking distance in the 6-min walk test trended to increase.

Conclusions: The study indicates that the anti-gravity treadmill training of patients with CMT should be pursued in larger CMT cohorts.

Original languageEnglish
JournalGenes, Brain and Behavior
Volume7
Issue number12
Pages (from-to)e00794
ISSN1601-1848
DOIs
Publication statusPublished - Dec 2017

    Research areas

  • Journal Article

ID: 52415135