Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Adherence to early pulmonary rehabilitation after COPD exacerbation and risk of hospital readmission: a secondary analysis of the COPD-EXA-REHAB study

Research output: Contribution to journalJournal articleResearchpeer-review

  1. High prevalence of exercise-induced stridor during Parkrun: a cross-sectional field-based evaluation

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Coronary heart disease and heart failure in asthma, COPD and asthma-COPD overlap

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 'Reduced' HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Trajectory of Preserved Ratio Impaired Spirometry: Natural History and Long-Term Prognosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Infographic. Benefits and harms of exercise therapy in people with multimorbidity

    Research output: Contribution to journalComment/debateResearchpeer-review

View graph of relations

BACKGROUND: Early pulmonary rehabilitation after exacerbation of chronic obstructive pulmonary disease (COPD) has previously been shown to reduce the risk of hospital admission and improve physical performance and quality of life. However, the impact of attendance at early rehabilitation programmes has not been established.

OBJECTIVES: To evaluate the impact of increasing attendance to pulmonary rehabilitation on the risk of hospital admission, physical performance and quality of life in patients attending an early rehabilitation programme after an exacerbation of COPD.

METHODS: This study was a secondary exploratory analysis of the randomised controlled trial COPD-EXA-REHAB study, involving patients hospitalised with an exacerbation of COPD. The COPD-EXA-REHAB study compared early pulmonary rehabilitation, starting within 2 weeks after an exacerbation, with standard treatment, that is, the same programme starting 2 months later. The present analysis included only the 70 patients allocated to early pulmonary rehabilitation.

RESULTS: At 1-year follow-up, we found an association between the number of sessions attended and a reduction in hospital admissions (incidence rate ratio 0.93 (95% CI 0.88 to 0.99), p=0.02), corresponding to a 7% reduction for each session attended. Similarly, at 2-month follow-up, physical performance was positively associated with sessions attended: the mean Incremental Shuttle Walk Test result improved by 8 m with each session (95% CI 2.54 to 13.56, p=0.005) and the Endurance Shuttle Walk Test result by 44 s (95% CI 18.41 to 68.95, p=0.001). Quality of life, assessed using the COPD Assessment Test, was not significantly associated with the number of attended sessions, with the average score increasing by 0.15 points with each session (95% CI -0.35 to 0.65, p=0.55).

CONCLUSION: Increased attendance at early pulmonary rehabilitation after exacerbation of COPD was associated with reduced risk of hospital admission and improved physical performance.

Original languageEnglish
JournalBMJ Open Respiratory Research
Volume7
Issue number1
Pages (from-to)1-6
Number of pages6
ISSN2052-4439
DOIs
Publication statusPublished - 19 Aug 2020

    Research areas

  • pulmonary rehabilitation, COPD exacerbations, exercise

ID: 61962269