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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis

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Expression of inducible nitric oxide synthase (iNOS) is greatly upregulated in the colonic mucosa of patients with collagenous and ulcerative colitis. As the transcription factor nuclear factor kappaB (NFkappaB) is a major inducer of iNOS gene expression, we compared activation and transcriptional activity of NFkappaB in colonic mucosal biopsies from these patients.
Original languageEnglish
JournalGut
Volume54
Issue number4
Pages (from-to)503-9
Number of pages7
ISSN0017-5749
DOIs
Publication statusPublished - 2005

    Research areas

  • Colitis, Collagenous, Colitis, Ulcerative, DNA-Binding Proteins, Epithelial Cells, Gene Expression Profiling, Humans, I-kappa B Kinase, Intestinal Mucosa, NF-kappa B, Nitric Oxide Synthase, Nitric Oxide Synthase Type II, Promoter Regions, Genetic, Protein-Serine-Threonine Kinases, Transcription, Genetic, Translocation, Genetic

ID: 32528227