Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Accuracy of frozen section diagnosis: a retrospective analysis of 4785 cases

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Primary antibiotic resistance of Helicobacter pylori strains among adults and children in a tertiary referral centre in Lithuania

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. A short history of microbial biofilms and biofilm infections

    Research output: Contribution to journalReviewResearchpeer-review

  3. Biofilms and host response - helpful or harmful

    Research output: Contribution to journalReviewResearchpeer-review

  4. Diagnosis of biofilm infections in cystic fibrosis patients

    Research output: Contribution to journalReviewResearchpeer-review

  1. Necrotic ulcer on the chin of a previously healthy 38-year-old woman

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Expression of FGFR3 during human testis development and in germ cell-derived tumours of young adults

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Osteitis in the dens of axis caused by Treponema pallidum

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
During a 1-year period 4785 intraoperative consultations were performed. The pathology reports were retrospectively reviewed to determine the accuracy of frozen section diagnosis in various tissue types. Skin for evaluation of section margins and axillary sentinel lymph nodes for evaluation of metastatic disease were most frequently sent for frozen section diagnosis. The number of discordant cases were 182, 178 were false negative and four were false positive. When frozen section diagnoses were compared with permanent section diagnoses, the overall diagnostic concordance was 95.1%. The number of deferred specimens was 57. The accuracy of frozen section diagnosis varied between tissue types, and axillary sentinel lymph nodes accounted for the greatest number of discordances. In conclusion, the frozen section diagnosis is a reliable method with varying concordance and deferral rates between tissue types. We suggest regular monitoring of the performance in frozen section diagnosis.
Original languageEnglish
JournalActa Pathologica Microbiologica et Immunologica Scandinavica
Volume119
Issue number4-5
Pages (from-to)259-62
Number of pages4
ISSN0903-4641
DOIs
Publication statusPublished - 2011

    Research areas

  • Denmark, False Negative Reactions, False Positive Reactions, Female, Frozen Sections, Humans, Intraoperative Period, Male, Pathology Department, Hospital, Reproducibility of Results, Retrospective Studies

ID: 33229826