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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor

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  • Martina Giovannella
  • Lorenzo Spinelli
  • Marco Pagliazzi
  • Davide Contini
  • Gorm Greisen
  • Udo M Weigel
  • Alessandro Torricelli
  • Turgut Durduran
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We have investigated the accuracy and precision of "the BabyLux device", a hybrid time-resolved near-infrared (TRS) and diffuse correlation spectroscopy (DCS) neuro-monitor for the pre-term infant. Numerical data with realistic noise were simulated and analyzed using the BabyLux device as a reference system and different experimental and analysis parameters. The results describe the limits for the precision and the accuracy to be expected. The dependence of these limits on different experimental conditions and choices of the analysis method is also described. Experiments demonstrate comparable values for precision with respect to the simulation results.

Original languageEnglish
Article number#360049
JournalBiomedical optics express
Volume10
Issue number5
Pages (from-to)2556-2579
Number of pages24
ISSN2156-7085
DOIs
Publication statusPublished - 1 May 2019

ID: 58061119