Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor

Martina Giovannella; Lorenzo Spinelli; Marco Pagliazzi; Davide Contini; Gorm Greisen; Udo M Weigel; Alessandro Torricelli; Turgut Durduran

doi:10.1364/BOE.10.002556

Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor

Martina Giovannella, Lorenzo Spinelli, Marco Pagliazzi, Davide Contini, Gorm Greisen, Udo M Weigel, Alessandro Torricelli, Turgut Durduran

Department of Neonatology

12 Citations (Scopus)

Abstract

We have investigated the accuracy and precision of "the BabyLux device", a hybrid time-resolved near-infrared (TRS) and diffuse correlation spectroscopy (DCS) neuro-monitor for the pre-term infant. Numerical data with realistic noise were simulated and analyzed using the BabyLux device as a reference system and different experimental and analysis parameters. The results describe the limits for the precision and the accuracy to be expected. The dependence of these limits on different experimental conditions and choices of the analysis method is also described. Experiments demonstrate comparable values for precision with respect to the simulation results.

Original language	English
Article number	#360049
Journal	Biomedical optics express
Volume	10
Issue number	5
Pages (from-to)	2556-2579
Number of pages	24
ISSN	2156-7085
DOIs	https://doi.org/10.1364/BOE.10.002556
Publication status	Published - 1 May 2019

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Giovannella, M., Spinelli, L., Pagliazzi, M., Contini, D., Greisen, G., Weigel, U. M., Torricelli, A., & Durduran, T. (2019). Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor. Biomedical optics express, 10(5), 2556-2579. Article #360049. https://doi.org/10.1364/BOE.10.002556

Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor. / Giovannella, Martina; Spinelli, Lorenzo; Pagliazzi, Marco et al.
In: Biomedical optics express, Vol. 10, No. 5, #360049, 01.05.2019, p. 2556-2579.

Research output: Contribution to journal › Journal article › Research › peer-review

Giovannella, M, Spinelli, L, Pagliazzi, M, Contini, D, Greisen, G, Weigel, UM, Torricelli, A & Durduran, T 2019, 'Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor', Biomedical optics express, vol. 10, no. 5, #360049, pp. 2556-2579. https://doi.org/10.1364/BOE.10.002556

Giovannella M, Spinelli L, Pagliazzi M, Contini D, Greisen G, Weigel UM et al. Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor. Biomedical optics express. 2019 May 1;10(5):2556-2579. #360049. doi: 10.1364/BOE.10.002556

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AU - Weigel, Udo M

AU - Torricelli, Alessandro

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Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor

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