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Acceptable Success Rate in Patients With Periprosthetic Knee Joint Infection Treated With Debridement, Antibiotics, and Implant Retention

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  1. Changes in Patient Satisfaction Following Total Joint Arthroplasty

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Incidence and Risk Factors for Stroke in Fast-Track Hip and Knee Arthroplasty-A Clinical Registry Study of 24,862 Procedures

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Changes in Patient Satisfaction Following Total Joint Arthroplasty

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The problem is not necessarily the data, it is the interpretation

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BACKGROUND: Acute periprosthetic joint infection (PJI) following primary total knee arthroplasty (TKA) surgery can be treated with debridement, antibiotics, and implant retention (DAIR). However, varying results have been reported in the literature and optimal timing of the procedure is still debated. In this retrospective cohort study, we investigate (a) success rate of DAIR for treating PJI following primary TKA surgery and (b) whether time after primary surgery until DAIR and (c) type of isolated microorganism influence outcome.

METHODS: Sixty-seven patients with PJI following primary TKA surgery treated with DAIR were identified. Patients with insufficient data and patients who did not fulfill Musculoskeletal Infection Society PJI criteria were excluded, leaving 58 patients for analysis. Minimum follow-up was 2 years. A DAIR was considered a success if the patient was infection free after 2 years.

RESULTS: The overall success rate of PJI treated with DAIR was 84%. Median time until DAIR was 21 days (7-1092). Thirty-four patients (59%) were revised within 28 days, 42 patients (72%) within 42 days, while 10 patients (17%) were revised more than 90 days after primary TKA surgery. The success rates were 85%, 88%, and 60%, respectively. In the patients revised within 90 days, our success rate was 90% (43/48) regardless of the involved microorganism.

CONCLUSION: We find DAIR to be a viable and safe treatment option for PJI following primary TKA surgery, when performed early after primary surgery and with the addition of a relevant postrevision antibiotic regime.

Original languageEnglish
JournalThe Journal of arthroplasty
Volume34
Issue number2
Pages (from-to)365-368
Number of pages4
ISSN0883-5403
DOIs
Publication statusPublished - 1 Feb 2019

    Research areas

  • Acute periprosthetic joint infection, debridement, prosthesis retention, revision knee arthroplasty, timing

ID: 55649869