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The Capital Region of Denmark - a part of Copenhagen University Hospital
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A randomized study evaluating cinacalcet to treat hypercalcemia in renal transplant recipients with persistent hyperparathyroidism

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  • P. Evenepoel
  • K. Cooper
  • H. Holdaas
  • P. Messa
  • G. Mourad
  • K. Olgaard
  • B. Rutkowski
  • H. Schaefer
  • H. Deng
  • J.V. Torregrosa
  • R.P. Wuthrich
  • S. Yue
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Persistent hyperparathyroidism (HPT) after kidney transplantation (KTx) is associated with hypercalcemia, hypophosphatemia and abnormally high levels of parathyroid hormone (PTH). In this randomized trial, cinacalcet was compared to placebo for the treatment of hypercalcemia in adult patients with persistent HPT after KTx. Subjects were randomized 1:1 to cinacalcet or placebo with randomization stratified by baseline corrected total serum calcium levels (11.2 mg/dL [2.80 mmol/L]). The primary end point was achievement of a mean corrected total serum calcium value
Original languageEnglish
JournalAm.J.Transplant.
Volume14
Issue number11
Pages (from-to)2545-2555
Number of pages11
Publication statusPublished - Nov 2014

    Research areas

  • Adult, Kidney Transplantation, Parathyroid Hormone

ID: 44823814