A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial

Bernard Chevalier; Carlo Dimario; Franz-Josef Neumann; Donald E Cutlip; David O Williams; John Ormiston; Eberhard Grube; Robert Whitbourn; Jessie Coe; Lewis B Schwartz; ZOMAXX I Investigators; Kari Saunamäki

doi:10.1002/ccd.24958

A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial

Bernard Chevalier, Carlo Dimario, Franz-Josef Neumann, Donald E Cutlip, David O Williams, John Ormiston, Eberhard Grube, Robert Whitbourn, Jessie Coe, Lewis B Schwartz, ZOMAXX I Investigators, Kari Saunamäki

6 Citations (Scopus)

Abstract

The ZOMAXX I trial tested the noninferiority of a zotarolimus-eluting coronary stent (ZoMaxx(™) ) when compared with a paclitaxel-eluting coronary stent (Taxus(™) Express(2™) ) in a randomized trial of percutaneous intervention for de novo coronary artery stenosis. Angiographic analysis at the primary endpoint of 9 months has been reported previously. The purpose of this follow-on analysis was to describe the clinical results of the ZoMaxx and Taxus cohorts of the ZOMAXX I trial after 5 years.

Original language	English
Journal	Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Volume	82
Issue number	7
Pages (from-to)	1039-47
Number of pages	9
ISSN	1522-1946
DOIs	https://doi.org/10.1002/ccd.24958
Publication status	Published - 1 Dec 2013

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Chevalier, B., Dimario, C., Neumann, F.-J., Cutlip, D. E., Williams, D. O., Ormiston, J., Grube, E., Whitbourn, R., Coe, J., Schwartz, L. B., ZOMAXX I Investigators, & Saunamäki, K. (2013). A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 82(7), 1039-47. https://doi.org/10.1002/ccd.24958

A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial. / Chevalier, Bernard; Dimario, Carlo; Neumann, Franz-Josef et al.
In: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Vol. 82, No. 7, 01.12.2013, p. 1039-47.

Research output: Contribution to journal › Journal article › Research › peer-review

Chevalier, B, Dimario, C, Neumann, F-J, Cutlip, DE, Williams, DO, Ormiston, J, Grube, E, Whitbourn, R, Coe, J, Schwartz, LB, ZOMAXX I Investigators & Saunamäki, K 2013, 'A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial', Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, vol. 82, no. 7, pp. 1039-47. https://doi.org/10.1002/ccd.24958

Chevalier B, Dimario C, Neumann FJ, Cutlip DE, Williams DO, Ormiston J et al. A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2013 Dec 1;82(7):1039-47. doi: 10.1002/ccd.24958

Chevalier, Bernard ; Dimario, Carlo ; Neumann, Franz-Josef et al. / A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries : five-year results from the ZOMAXX I trial. In: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2013 ; Vol. 82, No. 7. pp. 1039-47.

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abstract = "The ZOMAXX I trial tested the noninferiority of a zotarolimus-eluting coronary stent (ZoMaxx({\texttrademark}) ) when compared with a paclitaxel-eluting coronary stent (Taxus({\texttrademark}) Express(2{\texttrademark}) ) in a randomized trial of percutaneous intervention for de novo coronary artery stenosis. Angiographic analysis at the primary endpoint of 9 months has been reported previously. The purpose of this follow-on analysis was to describe the clinical results of the ZoMaxx and Taxus cohorts of the ZOMAXX I trial after 5 years.",

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A randomized, controlled, multicenter trial to evaluate the safety and efficacy of Zotarolimus- vs. Paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries: five-year results from the ZOMAXX I trial

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