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A portfolio of biologic self-injection devices in rheumatology: how patient involvement in device design can improve treatment experience

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van den Bemt, Bart J F ; Gettings, Lynda ; Domańska, Barbara ; Bruggraber, Richard ; Mountian, Irina ; Kristensen, Lars E. / A portfolio of biologic self-injection devices in rheumatology : how patient involvement in device design can improve treatment experience. In: Drug Delivery . 2019 ; Vol. 26, No. 1. pp. 384-392.

Bibtex

@article{88b965c1a552491da9498219e8b890d9,
title = "A portfolio of biologic self-injection devices in rheumatology: how patient involvement in device design can improve treatment experience",
abstract = "Biologic drugs (e.g. anti-tumor necrosis factors) are effective treatments for multiple chronic inflammatory diseases including rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis. Administration of biologic drugs is usually via subcutaneous self-injection, which provides many patient benefits compared to infusions including increased flexibility, reduced costs, and reduced caregiver burden. However, it is also associated with challenges such as needle phobia, patient treatment misconceptions and incorrect drug administration, and can be impacted by dexterity problems. Evidence suggests these problems, along with other drug administration challenges (e.g. patient forgetfulness, busy lifestyles, and polypharmacy), can reduce patient adherence to treatment. To combat these challenges, patient feedback has been used to develop a range of self-injection devices, including pre-filled syringes, pre-filled pens, and electronic injection devices. Providing different devices for drug administration gives patients the opportunity to choose a device that addresses the challenges they face as an individual. Research suggests involving patients in medical device development, providing patients with a choice of devices and enrolling individuals in patient support programs can empower patients to take control of their treatment journey. By providing a portfolio of self-injection devices, designed based on patient needs, patient experience will improve, potentially improving adherence and hence, long-term treatment outcomes.",
author = "{van den Bemt}, {Bart J F} and Lynda Gettings and Barbara Domańska and Richard Bruggraber and Irina Mountian and Kristensen, {Lars E}",
year = "2019",
month = "12",
doi = "10.1080/10717544.2019.1587043",
language = "English",
volume = "26",
pages = "384--392",
journal = "Drug Delivery",
issn = "1071-7544",
publisher = "Taylor & Francis Inc",
number = "1",

}

RIS

TY - JOUR

T1 - A portfolio of biologic self-injection devices in rheumatology

T2 - how patient involvement in device design can improve treatment experience

AU - van den Bemt, Bart J F

AU - Gettings, Lynda

AU - Domańska, Barbara

AU - Bruggraber, Richard

AU - Mountian, Irina

AU - Kristensen, Lars E

PY - 2019/12

Y1 - 2019/12

N2 - Biologic drugs (e.g. anti-tumor necrosis factors) are effective treatments for multiple chronic inflammatory diseases including rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis. Administration of biologic drugs is usually via subcutaneous self-injection, which provides many patient benefits compared to infusions including increased flexibility, reduced costs, and reduced caregiver burden. However, it is also associated with challenges such as needle phobia, patient treatment misconceptions and incorrect drug administration, and can be impacted by dexterity problems. Evidence suggests these problems, along with other drug administration challenges (e.g. patient forgetfulness, busy lifestyles, and polypharmacy), can reduce patient adherence to treatment. To combat these challenges, patient feedback has been used to develop a range of self-injection devices, including pre-filled syringes, pre-filled pens, and electronic injection devices. Providing different devices for drug administration gives patients the opportunity to choose a device that addresses the challenges they face as an individual. Research suggests involving patients in medical device development, providing patients with a choice of devices and enrolling individuals in patient support programs can empower patients to take control of their treatment journey. By providing a portfolio of self-injection devices, designed based on patient needs, patient experience will improve, potentially improving adherence and hence, long-term treatment outcomes.

AB - Biologic drugs (e.g. anti-tumor necrosis factors) are effective treatments for multiple chronic inflammatory diseases including rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis. Administration of biologic drugs is usually via subcutaneous self-injection, which provides many patient benefits compared to infusions including increased flexibility, reduced costs, and reduced caregiver burden. However, it is also associated with challenges such as needle phobia, patient treatment misconceptions and incorrect drug administration, and can be impacted by dexterity problems. Evidence suggests these problems, along with other drug administration challenges (e.g. patient forgetfulness, busy lifestyles, and polypharmacy), can reduce patient adherence to treatment. To combat these challenges, patient feedback has been used to develop a range of self-injection devices, including pre-filled syringes, pre-filled pens, and electronic injection devices. Providing different devices for drug administration gives patients the opportunity to choose a device that addresses the challenges they face as an individual. Research suggests involving patients in medical device development, providing patients with a choice of devices and enrolling individuals in patient support programs can empower patients to take control of their treatment journey. By providing a portfolio of self-injection devices, designed based on patient needs, patient experience will improve, potentially improving adherence and hence, long-term treatment outcomes.

U2 - 10.1080/10717544.2019.1587043

DO - 10.1080/10717544.2019.1587043

M3 - Journal article

VL - 26

SP - 384

EP - 392

JO - Drug Delivery

JF - Drug Delivery

SN - 1071-7544

IS - 1

ER -

ID: 57027414