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A novel knee prosthesis model of implant-related osteomyelitis in rats

Niels H Søe, Nina Vendel Jensen, Birgit Meinecke Nürnberg, Asger Lundorff Jensen, Janne Koch, Steen Seier Poulsen, Gerald Pier, Helle Krogh Johansen

23 Citations (Scopus)

Abstract

There have been numerous reports of animal models of osteomyelitis. Very few of these have been prosthesis models that imitate human conditions. We have developed a new rat model of implant-related osteomyelitis that mimics human osteomyelitis, to investigate the pathology of infection after orthopedic implant surgery.
Original languageEnglish
JournalActa Orthopaedica
Volume84
Issue number1
Pages (from-to)92-7
Number of pages6
ISSN1745-3674
DOIs
Publication statusPublished - Feb 2013

Keywords

  • Animals
  • Arthroplasty, Replacement, Knee
  • Disease Models, Animal
  • Humans
  • Knee Joint
  • Male
  • Osteomyelitis
  • Prosthesis-Related Infections
  • Rats
  • Rats, Sprague-Dawley
  • Staphylococcal Infections

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