A nation-wide twin study of social cognition in schizophrenia spectrum disorders

Cecilie K Lemvigh; Birte Y Glenthøj; Birgitte Fagerlund

doi:10.1038/s41537-022-00223-1

A nation-wide twin study of social cognition in schizophrenia spectrum disorders

Cecilie K Lemvigh, Birte Y Glenthøj, Birgitte Fagerlund

3 Citations (Scopus)

Abstract

We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in the ability to detect sarcasm. Impairments were also observed in the unaffected MZ co-twins, indicating that social cognitive deficits could be a genetic vulnerability indicator of the disease. Worse social cognition was associated with lower intelligence and higher levels of psychopathology in patients.

Original language	English
Article number	12
Journal	Schizophrenia (Heidelberg, Germany)
Volume	8
Issue number	1
Pages (from-to)	12
ISSN	2754-6993
DOIs	https://doi.org/10.1038/s41537-022-00223-1
Publication status	Published - Dec 2022

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A nation-wide twin study of social cognition in schizophrenia spectrum disorders

Abstract

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